微血管密度和基质金属蛋白酶-9的表达与胶质瘤病理分级的关系

目的　探讨微血管密度 (MVD)和基质金属蛋白酶 9(MMP 9)的表达与人脑胶质瘤恶性程度及预后的关系。方法　采用免疫组织化学SP法检测 5 8例不同病理分级的人脑胶质瘤及 10例正常脑组织标本中MMP 9和CD3 4 的表达 ,测定其阳性细胞数和阳性血管数。结果　胶质瘤中MMP 9表达于肿瘤细胞胞浆和血管内皮细胞 ;不同病理分级胶质瘤中MMP 9阳性表达率分别为Ⅰ级 4 2 .9% ,Ⅱ级 6 5 .0 % ,Ⅲ级 86 .7% ,Ⅳ级 88.9% ,显著高于正常脑组织 (P<0 .0 1) ,且与胶质瘤恶性程度呈正相关 (rs=0 .5 97,P <0 .0 5 ) ;不同病理分级胶质瘤中MVD存在显著性差异 (H =4 7.86 5 ,P <0 .0 5 )。结论　MVD和MMP 9的表达与胶质瘤恶性程度密切相关 ,可作为临床判断胶质瘤恶性程度、侵袭性及预后的重要指标。     

SMA沥青混合料粗集料用量的变化对路用性能的影响规律研究

SMA沥青路面结构混合料中粗骨料含量高是其显著特征之一,如何有效控制粗骨料含量,保证其骨架嵌挤密实结构的力学性能,其用量变化对沥青路面路用性能的影响规律如何,本文通过试验进行研究。     

罗德里格矩阵在盾构引导系统中的应用研究

空间三维坐标转换是盾构自动引导系统三棱镜模型的关键问题.将罗德里格矩阵用于盾构机姿态参数的计算当中,并用VC 6.0编写了基于三棱镜模型的盾构自动引导系统.解析了自动引导系统的数字模型.该系统在苏州地铁1号线某区间试验中运行稳定、仪器连接设置简单.罗德里格矩阵用于空间三维坐标转换有一定的实用性.     

Inferring origin–destination trip matrices from aggregate volumes on groups of links: a case study using volumes inferred from mobile phone data

The origin–destination matrix is an important source of information describing transport demand in a region. Most commonly used methods for matrix estimation use link volumes collected on a subset of links in order to update an existing matrix. Traditional volume data collection methods have significant shortcomings because of the high costs involved and the fact that detectors only provide status information at specified locations in the network. Better matrix estimates can be obtained when information is available about the overall distribution of traffic through time and space. Other existing technologies are not used in matrix estimation methods because they collect volume data aggregated on groups of links, rather than on single links. That is the case of mobile systems. Mobile phones sometimes cannot provide location accuracy for estimating flows on single links but do so on groups of links; in contrast, data can be acquired over a wider coverage without additional costs. This paper presents a methodology adapted to the concept of volume aggregated on groups of links in order to use any available volume data source in traditional matrix estimation methodologies. To calculate volume data, we have used a model that has had promising results in transforming phone call data into traffic movement data. The proposed methodology using vehicle volumes obtained by such a model is applied over a large real network as a case study. The experimental results reveal the efficiency and consistency of the solution proposed, making the alternative attractive for practical applications. Copyright © 2011 John Wiley & Sons, Ltd.     

地铁荷载下隧道土体沉降的灰色预测与分析

随着我国地铁建设的迅猛发展,地铁运营荷载造成软土地基的长期沉降问题引起了足够的重视。针对监测和观测时间的非等时性,文中采用牛顿二次插值多项式插值的方法建立了非等时距灰色理论模型GM(1,1)和GM(2,1),对上海地铁四号线一区段的沉降进行预测,并与实际监测沉降量进行了比较,结果表明,GM(2,1)较GM(1,1)有更高的精度。通过监测数据分析,发现其沉降速率上半年明显小于下半年,并给出了较为合理的解释。     

基于交互式多目标决策的船型技术经济评价决策系统

给出了一种新的交互式多目标决策方法。在对指标有偏好信息及客观熵信息输出权重基础上，以严格的最小二乘法为工具，建立确定指标权重的优化模型，从而为多目标决策问题寻求到一种行之有效的方法。通过采用传统层次分析方法相比较，证明该方法在船型论证等复杂多目标决策问题上是适用和可靠的。     

基于模糊层次分析法的沥青路面破损状况评价

在分析沥青路面破损类型的基础上,构建了沥青路面破损状况评价的指标体系。综合运用层次分析原理和模糊决策理论,建立了沥青路面破损状况评价的模糊层次分析模型,该模型的重点在于确定各评价因素的权重和构造评价矩阵,最后结合实例证明了该模型的可行性。     

静水压力作用的水下结构振动及声辐射

采用有限元／边界元方法开发了静水压力作用的水下结构振动与声辐射的计算程序。依据不同分析域的特点，对结构域和流体内域采用有限元方法，对流体外域采用边界元方法。分析了流体一结构相似特性，使通过对常规结构有限元分析程序中的参数作合理设置，使之能直接用于内域流体声学有限元分析。流体外域采用边界元方法，选取合适的格林函数，能够考虑无穷远和自由液面边界条件。流体对结构的作用表现附加质量和附加阻尼。采用FORTRAN代码计算外域流体附加质量和附加阻尼矩阵，采用结构有限元分析程序对结构和内域流体作有限元分析，采用DMAP代码将附加质量和附加阻尼同结构质量矩阵和阻尼矩阵相叠加，实现了流固耦合计算。通过几何刚度矩阵对结构刚度矩阵修正来考虑静水压力对结构声辐射的影响。     

Householder矩阵的性质及其等价表示

对Householder矩阵的特征值给出了3种不同的求法，对此矩阵的初等反射性质作出了具有几何意义的证明，并讨论了该矩阵的若干性质．还作出了此矩阵的一个等价表示及给出了一个特殊的线性变换，使得在此变换下的表示矩阵就是Householder矩阵.     

Pole location control design of an active suspension system with uncertain parameters

This paper addresses the problem of robust control design for an active suspension quarter-car model by means of state feedback gains. Specifically, the design of controllers that assure robust pole location of the closed-loop system inside a circular region on the left-hand side of complex plane is investigated. Three sufficient conditions for the existence of a robust stabilizing state feedback gain are presented as linear matrix inequalities: (i) the quadratic stability based gain; (ii) a recently published condition that uses an augmented space and has been here modified to cope with the pole location specification; (iii) a condition that uses an extended number of equations and yields a parameter-dependent state feedback gain. Unlike other parameter-dependent strategies, neither extensive gridding nor approximations are needed. In the suspension model, the sprung mass, the damper coefficient and the spring constant are considered as uncertain parameters belonging to a known interval (polytope type uncertainty). It is shown that the parameter-dependent gain proposed allows one to impose the closed-loop system pole locations that in some situations cannot be obtained with constant feedback gains.