基于信令数据的出行强度影响因素分析模型

为探究城市交通出行强度影响因素及不同因素的影响程度，本文从土地利用与交通基础设施建设两方面出发，分析包括土地利用混合指数，职住混合率熵指数，公共交通站点 500 m覆盖率，路网可达性等17个指标与出行强度的相关关系；基于相关系数和拟合优度分析，提取7个与出行强度强相关指标，基于所识别指标构建北京市中心城区出行强度多元回归模型.模型结果表明，职住混合率熵指数对出行强度的影响最为显著，公共交通站点覆盖率对出行强度的影响比道路网密度和可达性更为明显.此外，给出单一土地利用/交通基础设施指标对出行强度拟合结果的离群特征分析方法，用于评估不同区域基础设施供给与交通出行需求之间的平衡关系.     

Achieving transport modal split targets at intermodal freight hubs using a model predictive approach

The increase of international freight commerce is creating pressure on the existing transport network. Cooperation between the different transport parties (e.g., terminal managers, forwarders and transport providers) is required to increase the network throughput using the same infrastructure. The intermodal hubs are locations where cargo is stored and can switch transport modality while approaching the final destination. Decisions regarding cargo assignment are based on cargo properties. Cargo properties can be fixed (e.g., destination, volume, weight) or time varying (remaining time until due time or goods expiration date). The intermodal hub manager, with access to certain cargo information, can promote cooperation with and among different transport providers that pick up and deliver cargo at the hub. In this paper, cargo evolution at intermodal hubs is modeled based on a mass balance, taking into account hub cargo inflows and outflows, plus an update of the remaining time until cargo due time. Using this model, written in a state-space representation, we propose a model predictive approach to address the Modal Split Aware – Cargo Assignment Problem (MSA–CAP). The MSA–CAP concerns the cargo assignment to the available transport capacity such that the final destination can be reached on time while taking into consideration the transport modality used. The model predictive approach can anticipate cargo peaks at the hub and assigns cargo in advance, following a push of cargo towards the final destination approach. Through the addition of a modal split constraint it is possible to guide the daily cargo assignment to achieve a transport modal split target over a defined period of time. Numerical experiments illustrate the validity of these statements.     

Tyre/road noise damping characteristics using nomographs and fundamental vibroacoustical relationships

Several studies have successfully developed laboratory and field measurement techniques to estimate tyre/road noise damping characteristics. However, laboratory–field noise correlations of pavement types in the form of nomographs is essential to cognize the pavements’ acoustical properties from a practical perspective. A toolkit that readily provides field tyre/road noise intensity of different pavement materials is needed. Thus, the main objective of this study was to develop nomographs with relationships for tyre/road noise versus pavement materials’ viscoelastic–vibroacoustical properties. Isothermal and isochronal nomographs of phase angle–tyre/road noise as toolkits were developed based upon well-established phase angle and noise intensities typical of mixtures, making the nomograph correlations very authentic, realistic, and novel along with benefit to predict tyre/road noise at any desired temperature and traffic speed (or frequency) combination. This study is envisaged to benefit in the discernment of road materials’ damping capabilities from vibroacoustical and field noise–viscoelastic relation aspects.     

基于隧道检测钢筋分布不均状况下判定衬砌结构安全性应用研究

近年来隧道内出现的越来越多的质量安全事故,引起各方高度重视,相应的最适宜隧道主体工程衬砌质量控制的地质雷达无损检测方法被广泛应用。通过雷达无损检测可揭露出衬砌内欠厚、脱空、钢筋分布不均等大量各类型缺陷,针对欠厚脱空等缺陷制定的注浆或开窗等治理措施是目前工程中常见的整改闭合工序,但钢筋分布不均对结构安全影响如何判定,怎么界定处理尚无成熟方案与规定。本文针对隧道项目中实际检测出的钢筋分布不均缺陷,在不宜大范围扰动结构及围岩进行整治的情况下,以及在避免其他问题共存等不利因素的前提下,应用有限元数值模拟计算分析强度安全系数,并结合现场外观等综合因素对衬砌结构安全性进行分析判定研究。     

提高公路路面摊铺平整度的方法探析

公路路面施工质量和行车舒适性主要通过公路路面摊铺平整度来反映。通过对公路路面平整度的影响因素进行分析，探讨提高公路路面摊铺平整度的方法，可为相关公路施工提供参考。     

废气旁通阀开度对增压直喷汽油机部分负荷性能的影响

汽油机节气门产生的节流损失对增压发动机泵气损失的影响相当严重,尤其是在中小负荷时,针对这一问题采用试验的方法研究了中小负荷下旁通阀开度对增压直喷汽油机性能的影响。研究结果表明,在节气门开度较小的小负荷工况下,涡轮增压器不宜工作,否则排气背压过大,对发动机非常不利;而废气旁通阀全开可以减小排气背压,能使发动机的动力性和经济性提高3%左右。对废气旁通阀的合理控制可以实现发动机在自然吸气和涡轮增压两种模式之间的转换。     

健胃愈疡颗粒对慢性胃炎伴幽门螺杆菌感染胃黏膜PAF、PS2的表达及对上皮细胞凋亡的影响

目的观察健胃愈疡颗粒(JWYY)对幽门螺杆菌相关性胃炎胃黏膜乳癌相关肽(PS2)和血小板活化因子(plate-let activating factor,PAF)表达的变化,并分析其可能的作用机制。方法80例幽门螺杆菌感染慢性胃炎患者随机分为2组,治疗组42例给予健胃愈疡颗粒治疗,对照组38例给予西药三联药物治疗。应用胃镜下活检胃黏膜组织快速尿素酶和Warthin-Starry染色法检测幽门螺杆菌,应用Western blot检测PS2、PAF表达变化。应用末端转移酶介导的dUTP切口末段标记法(TUNEL)检测细胞凋亡。第4周复查胃镜。结果治疗组凋亡指数明显比对照组减少(P<0.05),治疗组总有效率高于对照组(P<0.05)。Western blot检测显示:JWYY颗粒可上调PS2并下调PAF的表达,而对照组对胃黏膜PS2和PAF的表达影响不大。结论健胃愈疡颗粒治疗幽门螺杆菌(Hp)相关性胃炎可能与杀灭Hp、上调PS2和下调PAF的表达来抑制细胞凋亡有关。     

油底壳有限元模态分析及实验验证

以EQ491型发动机油底壳为研究对象,通过有限元法得到了油底壳模型的固有频率和振型,运用模态实验技术,验证了有限元模型的合理性。在原始有限元模型的基础上,对油底壳模型进行约束模态分析,验证了油底壳结构的合理性,即油底壳固有频率远大于发动机机体激振频率。     

EGFR、Ku70、NF-κB及Bcl-2在Graves病中的表达及意义

目的研究Graves病患者细针穿刺组织中EGFR、Ku70、NF-κB和Bcl-2基因的表达水平,探讨其在Graves病发生发展中的作用。方法 Graves病组患者59例,平均年龄(44.66+12.94)岁,其中男16例,女43例;甲状腺结节周围正常甲状腺组织标本27例为对照组,平均年龄(44.64+14.27)岁,其中男6例,女21例。采用实时荧光定量逆转录-多聚酶链反应(RT-PCR)法检测EGFR、Ku70、NF-κB和Bcl-2在Graves病及对照组甲状腺组织中的表达,t检验分析基因表达水平差异;Pearson相关法分析基因表达与临床特征及相关血清学指标之间的关系。结果上述基因在对照组及Graves病甲状腺组织中都有不同程度的表达。Graves病患者组织中EGFR及Ku70的表达水平明显高于对照组甲状腺组织(1.752±0.660 vs.0.859±0.125,P<0.05;3.304±0.402 vs.0.768±0.102,P<0.001);NF-κB及Bcl-2的表达水平明显低于对照组甲状腺组织(0.578±0.066 vs.0.884±0.085,P<0.001;0.834±0.086vs.1.235±0.261,P<0.05)。Graves病组织中NF-κB与Bcl-2表达水平呈正相关(r=0.399,P<0.001)。Graves病组织中Ku70的表达水平与血清TgAb水平呈正相关(r=0.263,P<0.05),而其他基因表达与相关血清学指标无关(P均>0.05)。结论 Ku70、EGFR、NF-κB、Bcl-2介导的信号转导通路可能参与了Graves病的发生、发展过程。