关于对牛顿环测量球面弧半径误差的探讨

通过用牛不测量球面弧半径误差的讨论，说明用干涉法代替机械法测量透镜的半径具有更高的准确度，并指出它的实际意义。     

用火焰原子吸收光谱法测定镁合金中的锌

将镁合金样品用盐酸消化。加入释放剂氯化锶消除硅的干扰，用火焰原子吸收光谱法测定样品中锌的含量。对灯电流、乙炔流量、观测高度、酸及其用量、共存元素和镁基体等影响锌测定的因素进行了考察并予以优化。采用火焰原子吸收光谱法的标准曲线法进行测定，线性范围为1．0～10．0mglg、检出限为21μg/L、相对标准偏差（n=11）小于0．5％。应用此法对镁合金标准样品进行了分析。结果表明精密度和准确度均符合国家标准分析方法的要求。     

Rapid quantification of the metabolite of valacyclovir hydrochloride in human plasma by liquid chromatography-tandem mass spectrometry

Objective To establish a rapid, sensitive and selective liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the determination of acyclovir (the metabolite of valacyclovir hydrochloride) in human plasma. Methods After addition of ganciclovir as internal standard (IS), plasma samples were prepared by one-step protein precipitation using acetonitrile as precipitant, followed by an isocratic elution with 0.1% formic acid 3.5μm) column. Detection was performed on a triple-quadrupole mass spectrometer utilizing electrospray ionization (ESI) interface operating in positive ion and selected reaction monitoring (SRM) mode with the precursor to product ion transitions m/z 226.2→152.1 for acyclovir and m/z 256.2→152.1 for the IS. Results The analytical results demonstrated a good linearity over the ranges from 0.005 to 4μg/mL (r=0.9999) for valacyclovir hydrochloride. The relative standard deviations (RSD) of intra-batch and inter-batch were less than 4.06% and 9.23%, respectively. The limit of detection and lower limit of quantification in human plasma were 2ng/mL and 5ng/mL, respectively. Conclusion The method was simple, sensitive, accurate and reproducible and has been successfully applied to a bioequivalence study of valacyclovir hydrochloride capsules in Chinese healthy male volunteers.     

关于对牛顿环测量球面弧半径误差的探讨

通过用牛顿环测量球面弧半径误差的讨论,说明用干涉法代替机械法测量透镜的半径具有更高的准确度,并指出它的实际意义.     

高精度的测回水平方向标准偏差值的测量

一测回水平方面标准差值是个综合性误差值。其值的大小量衡量一台测绘仪器检定合格与否的重要参数之一。我院仪修厂在长期的仪器检修实践中，总结出一套测出高精度的一测回水平方向标准偏差值的方法。     

A rapid method for the determination of dopamine in porcine muscle by pre-column derivatization and HPLC with fluorescence detection

A rapid method has been developed based on the sample preparation procedure named as QuEChERS （Quick, Easy, Cheap, Effective, Rugged and Safe）, combined with reversed-phase high performance liquid chromatography with fluorescence detector and C18 column after precolumn derivatization using o-phthalaldehyde and 2-mercaptoethanol to determine dopamine in porcine muscle. Methanol and deionized water （0.1% acetic acid, v/v） with a ratio of 60：40 was used as mobile phase. The flow rate was 0.8 mL/min and dopamine was eluted within 15 min. The linearity range was 0.003-8 μg/mL with r=0.9992. The detection limit for dopamine was 4 μg/kg and the quantification limit was 9 μg/kg. Recovery studies were carried out at 0.1, 0.5 and 1.0 mg/kg fortification levels and the average recoveries obtained ranged from 90.4% to 98.2% with relative standard deviations between 3.5% and 8.1%. The method was found to be suitable for detection of dopamine in animal product tissues at the maximum residue level.     

用电感耦合等离子体原子发射光谱法测定铝锡合金中的铜和锡

将铝锡合金样品用盐酸-过氧化氢溶解后,以电感耦合等离子体原子发射光谱法同时测定样品中铜和锡的含量。对等离子体原子发射光谱仪的分析线、高频强度、载气流量、观测高度、背景、溶样酸的种类及其用量、铝基体等影响铜、锡测定的因素进行了试验并予以优化。结果表明,线性范围：铜为5.0～30.00mg/g、锡为15.0～270.0mg/g;检出限：铜为0.11mg/g、锡为3.06mg/g;相对标准偏差（n=11）：铜为0.85%、锡为1.03%。用电感耦合等离子体原子发射光谱法分析了铝锡合金标准样品。结果表明,该方法的精密度和准确度均符合GB/T20975.25—2008的要求。     

国Ⅱ阶段轻型汽车排放的生产一致性调查分析

收集了74种轻型车新车排放生产一致性试验数据,从轻型车排放生产一致性评价的定义出发,对其影响因素进行了统计分析和研究。统计量及标准偏差分布数据表明,目前我国国Ⅱ阶段轻型车新车的排放处于低排放水平;不同车型之间的生产一致性控制水平存在差异,影响生产一致性的主要因素是生产标准偏差。     

受电子接触网间接触压力的分析

介绍了几条电气化铁路受电弓与接触网间（以下简称弓网间）接触压力情况，并根据接触网检测车的检测结果对其进行分析。     

评价过程能力的普遍性原则及其应用（二）

4两种能力评定方法之比较——实例由质量特性值随机样本生成的直方图,即使显示与正态分布规律严重不符的状态,但在执行前述