SUPPRESSION OF GROWTH OF A HUMAN LIVER－DERIVED CELL LINE BY ENDOGENOUSLY PRODUCED PARATHYROID HORMONE－RELATED PEPTIDE

ＳＵＰＰＲＥＳＳＩＯＮＯＦＧＲＯＷＴＨＯＦＡＨＵＭＡＮＬＩＶＥＲ－ＤＥＲＩＶＥＤＣＥＬＬＬＩＮＥＢＹＥＮＤＯＧＥＮＯＵＳＬＹＰＲＯＤＵＣＥＤＰＡＲＡＴＨＹＲＯＩＤＨＯＲＭＯＮＥ－ＲＥＬＡＴＥＤ　ＰＥＰＴＩＤＥＬＩＨｕｓｏｎｇ；Ｐ．Ｋ．Ｓｅｉｔｚ，Ｐ．...     

“营养状况评价图”及Kaup指数在西安地区应用的比较

作者报告了西安市雁塔区城区及郊区1～5岁儿童生长发育监测结果。其体重较1985年西安市横断面调查研究的结果增高,身高无明显变化;城区儿童体重及身高均高于郊区农村儿童;应用Kaup指数及“营养状况评价图”评价结果显示,Kauq指数评价西安市儿童的营养状况更接近干实际情况。     

基于疲劳累积损伤的弹塑性裂纹扩展分析

根据裂尖疲劳损伤累积导致材料破坏的观点,发展了一个弹塑性疲劳裂纹扩展模型. 假设在裂纹前缘HRR场内存在一个高应变区,该区长度x*等于材料常数D、其塑性 变程是△尹,由N区朋on公式求出对应于△a*的疲劳破坏循环数N白,则疲劳裂纹扩 展速率就是x‘/N,。新模型建立了材料低周疲劳特性与弹塑性裂纹扩展规律之间的 联系。由模型计算得到的弹塑性裂纹扩展速率与实验结果的比较表明,二者吻合良 好。      

越南Ha Nam省近十年来土地利用变化研究

采用单一土地利用动态度、土地利用度、Gibbs-Martin多样化指数、城市扩展强度、人口一城市扩展指数等定量指标,对越南Ha Nam省近10年来的土地利用变化进行了探讨.结果表明:2000-2010年,越南Ha Nam省土地利用发生了大幅度的变化.     

增殖抑制基因和血管内皮生长因子在胃癌中的表达及其意义

目的探讨增殖抑制基因(HSG)以及血管内皮生长因子(VEGF)在胃癌中的表达及其意义。方法采用免疫组化法检测HSG和VEGF在胃正常黏膜、癌旁组织及胃癌组织中的表达。结果胃正常黏膜、癌旁组织及胃癌组织HSG的阳性表达率分别为66.7%、58.0%和38.3%,正常黏膜组到胃癌组HSG表达率呈递减趋势,差异有统计学意义(P<0.05);VEGF在3组中的阳性表达率分别为13.3%、20.0%和68.3%,正常黏膜组到胃癌组的表达率呈递增趋势,差异有统计学意义(P<0.05);Spearman等级相关分析显示,HSG与VEGF表达呈负相关(r=-0.847,P<0.05)。结论 HSG与VEGF的过表达可能是胃癌发生发展以及转移的重要原因之一。     

Logistics as a driving force for development under the Belt and Road Initiative – the Chinese model for developing countries

ABSTRACT

An important objective of “the Belt and Road Initiative” is to promote the economic growth of countries in the region. China’s successful development experience, proposed in the initial stage of reform, can be summarised as “Looking for development, building the highway first”. This study is the first to evaluate whether logistics infrastructure has indeed contributed to economic growth by employing an error correction model with panel data from 2003 to 2014. In addition, we compare the influence levels of different sectors of logistics infrastructure in different regions, i.e. developed and developing regions. We focus on developing regions as they represent good development experiences for developing countries in the Silk Road Economic Belt. For developing regions, we find that the most influential factors are telecommunication and airway transportation, which should be the foci of attention in order to promote economic growth and reduce inter-region economic inequalities. The research confirms that logistics is indeed a driving force for economic growth in China, and that the contributions of specific sectors can be a useful reference for developing countries to determine prioritisation of investment in different logistics sectors across regions.     

Transport infrastructure and long-run economic growth in OECD countries

This paper provides an empirical evaluation of the growth impact of public infrastructure in a panel of 18 OECD countries during 1870–2009. This study goes beyond the traditional analysis of growth accounting models by exploring the indirect effect of stock of core infrastructure on output growth through its impact on productivity. Constructing a long-run historical dataset on infrastructural capital formation spanning from 1870, estimated results show that growth in both labour productivity and total factor productivity are positively, but not substantially, influenced by growth in the stock of infrastructure. Furthermore, applying the system GMM technique (Generalised Method of Moments) revels that although rate of returns to investment in infrastructure exceed the private rate in OECD countries, it is not as high as positive externalities associated with investment in equipment and structure investment.     

船用汽轮机转子疲劳裂纹扩展寿命分析

分析汽轮机转子疲劳裂纹扩展寿命各种随机变量的统计分布规律和参数估计,给出计算裂纹扩展寿命的Monte-Carlo模拟仿真过程,运用Miner法则分析循环载荷下的疲劳裂纹扩展寿命评估方法,以某型转子的计算实例证明概率断裂力学方法的有效性。     

氧化苦参碱在大鼠肾间质纤维化进程中的保护作用

目的探讨氧化苦参碱对大鼠肾间质纤维化进程的干预作用,并阐明其部分机制。方法40只雄性SD大鼠,随机分为假手术组、模型组、苯那普利组、氧化苦参碱大剂量组和小剂量组。以单侧输尿管结扎术建立输尿管梗阻的动物模型。术后第14天取术侧肾组织行HE、Masson染色及转化生长因子-β1(TGF-β1)、α-平滑肌肌动蛋白(-αSMA)和Ⅲ型胶原(ColⅢ)免疫组化检测,并运用图像分析系统做半定量分析。结果经氧化苦参碱干预后,梗阻侧肾脏的-αSMA、TGF-β1和ColⅢ的表达均显著低于模型组(P<0.01);大剂量氧化苦参碱组均低于苯那普利组(P<0.05);氧化苦参碱大剂量组和小剂量组之间无显著性差异(P>0.05)。结论氧化苦参碱可能是通过降低TGF-β1等细胞因子的表达而减少细胞外基质(ECM)产生细胞的活化,从而减少ECM的沉积,达到抗肾间质纤维化的作用。     

脑缺血组织nestin蛋白重新表达及其与碱性成纤维细胞生长因子表达的关系

目的　研究缺血脑组织nestin蛋白重新表达和碱性成纤维细胞生长因子 (bFGF)表达的关系。方法　建立永久性脑缺血大鼠模型 ,采用免疫组化染色方法 ,观察脑缺血后 1、3、7、14、2 8d脑组织nestin蛋白和bFGF的表达。结果　缺血后 1～ 3d缺血灶附近nestin免疫阳性细胞大量出现 ,缺血 7d开始减少 ;而bFGF免疫阳性细胞在缺血 14d大量出现 ,缺血 2 8d开始减少。结论　缺血脑组织重新表达nestin蛋白不需要bFGF的营养和支持 ,缺血脑组织周围的nestin免疫阳性细胞来源于重演胚胎发育过程的星形胶质细胞