Generalized Maximum Benefit Multiple Chinese Postman Problem

This research is focused on a generalization on the Max Benefit Chinese Postman Problem and the multiple vehicle variant of the Chinese Postman Problem. We call this generalization, the Generalized Maximum Benefit k-Chinese Postman Problem (GB k-CPP). We present a novel Mixed Integer Programming (MIP) formulation for the GB k-CPP. Four different cases of the model are discussed. The first case, performs arc-routing with profits and assumes that the origin and destination for each vehicle is the same for each cycle and is given by the user. The next case relaxes the assumption that the origin and destination for each vehicle should be the same and allows the users to select possible origins/destinations for vehicles. Case three gets the origin for each vehicle as input and produces a solution based on finding the best destination for each vehicle. The last case, that is very general, allows the optimization model to select possibly different locations for vehicle origin and destination, during each cycle. The different cases are applied to a security patrolling case conducted on the network of University of Maryland at College Park campus and the results are compared.     

浅议高职语文教学所面临的问题及其对策

高职院校培养的是适应当前及未来社会发展需求的高素质应用性专门人才,客观上要求毕业生应具备较好的汉语阅读、口语、书面语和汉字书写等语文基本技能。但由于种种原因,目前高职院校在培养和提高学生这些素质方面存在不少问题,文章对此作了分析,并提出相应的对策。     

Effect of ABCA1-V771M polymorphism on plasma lipid levels and its relationship with coronary atherosclerotic heart disease

Objective To explore the risk association of ABCA1-V771M polymorphism with coronary heart disease (CHD) in Hart nationality in Northwest of China. Methods With case-control study, ABCA1-V771M polymorphism was detected in 204 unrelated Hart nationality people in Northwest of China, and all the subjects by coronary angiography were grouped into 106 cases and 98 controls. The genotypes and alleles frequency distribution of ABCA1-V771M polymorphisms were analyzed by PCR-RFLP analysis, and the clinical statistics of serum lipids were compared and its effects of ABCA1-V771M polymorphism on the plasma lipid levels and coronary atherosclerotic heart disease were analyzed. Results The genotypic frequencies of ABCA1-V771M polymorphism matched well under Hardy-Weinberg equilibrium (P>0.05), V and M allelic frequencies were 33.3% and 66.7%. In comparison with VV VM genotype carriers, MM genotypes carriers had much lower plasma levels of HDL-C (P<0. 001) and much higher plasma levels of TG (P<0. 05). M allelic frequency in CHD group was significantly higher than V allelic frequency (P<0. 05). M allele was related with more severity of atherosclerosis in the coronary artery than V allele (P<0.05). However, there was no obvious difference in the incidence of AMI among carriers with three genotypes of ABCA1-V771M polymorphism (P>0.05). Conclusion ABCA1-V771M polymorphism was not only associated with the plasma levels of HDL-C and TG, but also related to the susceptibility and severity of coronary atheroselerotic heart disease. Moreover, M771 allele appeared to be atherogenie among Han population in Northwest of China.     

健胃愈疡颗粒对慢性胃炎伴幽门螺杆菌感染胃黏膜PAF、PS2的表达及对上皮细胞凋亡的影响

目的观察健胃愈疡颗粒(JWYY)对幽门螺杆菌相关性胃炎胃黏膜乳癌相关肽(PS2)和血小板活化因子(plate-let activating factor,PAF)表达的变化,并分析其可能的作用机制。方法80例幽门螺杆菌感染慢性胃炎患者随机分为2组,治疗组42例给予健胃愈疡颗粒治疗,对照组38例给予西药三联药物治疗。应用胃镜下活检胃黏膜组织快速尿素酶和Warthin-Starry染色法检测幽门螺杆菌,应用Western blot检测PS2、PAF表达变化。应用末端转移酶介导的dUTP切口末段标记法(TUNEL)检测细胞凋亡。第4周复查胃镜。结果治疗组凋亡指数明显比对照组减少(P<0.05),治疗组总有效率高于对照组(P<0.05)。Western blot检测显示:JWYY颗粒可上调PS2并下调PAF的表达,而对照组对胃黏膜PS2和PAF的表达影响不大。结论健胃愈疡颗粒治疗幽门螺杆菌(Hp)相关性胃炎可能与杀灭Hp、上调PS2和下调PAF的表达来抑制细胞凋亡有关。     

采用C型独立液货舱的超大型乙烷运输船(VLEC)研究

美国的页岩气繁荣发展在中短期内将造成乙烷供应的不断增长,将带来对欧洲及亚洲地区大宗出口的机遇;而全球乙烷运输需求的增长和船东对船舶经济性要求的提高,让超大型乙烷运输船(VLEC)应运而生。论文对VLEC的船型方案进行了比较分析,重点研究采用C型独立液货舱围护系统的VLEC的液罐设计方法,通过对采用碟形封头的总舱容为81 500 m3和采用球形封头的总舱容为75 500 m3的VLEC船型进行方案设计和研究,论证了论文提出的采用C型独立液货舱的超大型乙烷运输船这一方案的可行性。     

中医理论的经济学应用初探

简述了中医精气神学说,结合经济学知识提出了企业的精气神概念;对企业主要职能部门作了五行分形,利用五行相生相克分析了各功能区的相互依存与制约关系.     

时速350 km中国标准动车组车载天线的隔离度及最小排布间距

基于中国标准动车组车载终端设备的部署现状和未来规划,调研其采用的通信系统类型、车载天线的工作频率和安装数量;以900MHz频段GSM-R系统、450MHz频段和2 100MHz频段LTE-R系统为例,对车载终端的杂散干扰进行理论分析,基于自由空间损耗理论模型计算、电磁软件仿真模拟和试验平台实测的结果,研究车载天线的隔离...     

不同冷却方式对大尺寸钢板感应加热成形的影响

为有效解决船用中厚钢板复杂曲面加工问题,本文探究了空气冷却、正面水冷和反面水冷方式对大尺寸钢板弯曲成型的影响因素。首先采用COMSOL Multiphysics仿真平台模拟了电磁感应加热和冷却变形多物理场同步耦合过程,然后分析了各种因素对大尺寸钢板弯曲成型影响,最后通过实验验证了有限元模型的可靠性,并对感应加热弯曲成型效果进行评估。研究结果表明:(1)相对于水冷,空冷对钢板Y向位移改变效果显著。(2)相对于空冷,水冷对钢板角位移的改变影响明显。(3)当频率为50kHz时,电流频率对表面温度和角位移影响显著。(4)当钢板长宽比≥1:2时,Y向位移的增加比较显著;当长宽比≈1:1时,角位移的改变比较明显。     

多模块连接半潜式平台稳性对比分析

为开发我国海洋丰富的渔业、油气和旅游资源,可以在指定海域布设超大型浮式结构物,作为综合保障基地,提供船舶停靠、人员居住、渔业加工、油气开发、环境监测、飞机起降等多种功能.考虑到建造、运输等因素,超大型浮式结构物一般由多个相同或相似模块连接组成.本文基于一型半潜式平台模块,分别开展单、双、三模块的稳性分析,并对其稳性分析结果进行对比分析,探讨模块数量对平台稳性的影响,为超大型浮式结构物的后续设计与运营提供参考.     

金融危机对中国航运业及中国海事的影响之追踪

文中以广州南沙港区为例,通过大量的数据分析,讨论了金融危机对中国航运业所带来的冲击,以及对中国海事监管造成的影响。建议在当前形势下,中国航运业和中国海事都要紧紧抓住危机中蕴含的机遇,谋发展、求提升。