陕西关中人群骨质疏松性骨折与细胞色素P450芳香化酶编码基因的关联分析

目的 探讨骨质疏松性髋部骨折(osteoporotic hip fracture, OHF)与细胞色素P450芳香化酶编码基因(cytochrome P450c19, CYP19)多态性的关系.方法 采用群体关联分析的方法,对来自陕西关中人群的400例OHF患者和400例正常对照的7个单核苷酸多态性(single nucleotide polymorphisms, SNP)位点进行了分型实验和单体型的病例-对照研究.结果 共700个个体分型成功,haploview关联分析识别出了3个单体域的单体型,并挑选出7个标签SNP.方差分析的结果表明,位于CYP19基因的SNP位点rs643892和rs3781590以及单体域3区多态性与髋部骨折之间存在相关性.结论 细胞色素P450芳香化酶编码基因和我们所研究的陕西关中汉族群体的骨质疏松性骨折(osteoporotic fracture, OF)发病率关联.细胞色素P450芳香化酶编码基因可能对中国陕西关中汉族人群OHF的发病率有影响.     

上海世博会停车换乘交通组织

为实现上海世博交通集约化组织目标、降低自驾游客出行比例,建设世博停车换乘设施并组织引导自驾游客采取P＋R模式前往世博园区最有效措施之一。借鉴日本爱知世博会等大型公共活动停车换乘组织经验,提出上海世博会P＋R交通组织基本思路,将服务对象划分为一日往返自驾游客和本地化自驾游客两类。分析P＋R泊位需求的影响因素,并进行规模预测,得到两类游客的泊位需求总体规模和空间分布。最后,提出分三个层次设置P＋R设施以及完善世博P＋R配套设施和政策的具体建议。     

轨道交通站点综合开发模式探讨

为推动旧城改造与新城发展,解决目前地铁高投入低回报的公益性给建设方带来的巨大资金压力问题。通过总结已运营的地铁线对城市发展的影响,探讨以轨道交通建设为契机、在TOD理念指导下的综合开发模式,并提出轨道交通站点与周边地块综合开发理念、综合开发类型,以其良好的收益来减少地铁建设的资金压力。     

运用于京沪高铁动车组中WTD技术的改进

车载无线传输网关（WTD）技术通过对车辆的实时信息进行采集,处理及发送,使得在地面接收端的信息处理系统能够有效地监控与管理动车组.京沪高铁通信环境的变化对现有WTD技术提出了更高要求.本文通过引入有限状态机技术,类P2P文件传输技术,使得改进后的WTD技术能够在这种新的高速铁路环境下发挥更大的作用.     

港口竞争力评价模型研究

随着港口间的竞争日益加剧和港口功能的拓展,港口竞争力所涉及的范围也日益变化,在此背景下,对港口竞争力进行研究就显得尤为重要。为了对港口竞争力进行分析,本文针对港口指标多输入多输出的特点,应用数据包络分析方法,分别引入C2R和C2GS2模型,对中国主要港口竞争力进行评价,以期找出非有效性的港口,并对其提出改进建议。作者根据实际港口输入输出数据指标,对10个港口进行了有效性评价,结果表明DEA用于港口竞争力评价是有效的。     

公共交通引导的城市空间增长研究——波特兰“精明增长”实践给我们的启示

通过城市公共交通与城市空间增长互动关系的论证,笔者认为运用TOD发展模式引导未来中国大城市空间增长朝着紧凑、集约形态发展具有举足轻重的实际意义.波特兰城市空间”精明增长”实践中突出强调了公共交通对城市用地的引导作用,通过强化城市大运量轨道交通与用地有机结合、复合型用地形态的组合,在西区开发过程中取得了良好的效果.文章借鉴波特兰的城市空间增长实践,结合长春市的城市空间发展现状,分析认为长春市目前仍处于简单外延式空间扩展阶段,为实现城市空间理性发展,应确立以立公共交通为导向的空间发展模式,同时应该完善微观规划设计并建立相应的政策保障体系.     

基于车联网V2P 的行人碰撞风险辨识研究

为探索基于车联网V2P(Vehicle to Pedestrian)通信技术的行人碰撞风险辨识方法, 首先,在车联网环境下实时获取了目标位置、速度、运动方向等信息,并分析了典型人-车相 对运动场景中交通参与者的行为不确定性,进而提出了人-车碰撞区域随机几何模型;然后, 综合考虑了车联网系统的通信延时、定位误差、人-车相对运动不确定性等多因素的影响,建 立了人-车碰撞事故概率和冲突风险程度模型;最后,通过仿真实验分析了行车速度、通信延 时、定位精度等因素对行人碰撞风险辨识模型效果的影响,以及各因素间的相关性关系.本文 提出的方法对行人安全保护研究具有一定的参考价值,研究结果同时指出了车联网系统通信 延时与定位精度的技术要求.     

Environmental innovation and the role of stakeholder collaboration in West Coast port gateways

The paper explores the role of stakeholder collaboration in the adoption of innovations as part of the environmental and sustainability agenda of port gateways. We do this through a comparative assessment of the port of Vancouver, British Columbia, and the twin ports of Los Angeles and Long Beach, California. An inductive research approach is used to identify and assess the initiation and implementation process behind exemplary innovations. Innovation includes new technologies and processes for handling and moving cargo, mechanisms for planning and policy making, as well as financing, implementing, upgrading, managing and operating infrastructure systems. A relatively new arena for competition on the basis of innovation concerns environmental performance. The conceptual framework and empirical evidence suggest that while there may be intense demand for and supply of innovation in port gateways, the complex dynamics of the logistics chain are such that successful innovation requires conscious involvement and collaboration of stakeholders.     

Cooperation among freight forwarders: Mode choice and intermodal freight transport

The objective of this paper is to compare vertical and horizontal cooperation among freight forwarders. The paper analyses three freight forwarders (‘players’) with two different means of transportation. The first two players are truck-operating freight forwarders. The third player is a freight forwarder with its own ship. For the purposes of analysis, the paper applied a two-stage game. The results revealed that the best form of cooperation is the one in which the large truck-operating company would establish a coalition with the ship-operating company; that is, vertical cooperation. This cooperation would generate better payoffs in the form of profit, not only to the members of this coalition, but also to the player that has not joined the coalition. However, user surplus is negative in all coalitions, which shows that the establishment of these kinds of cooperation is not beneficial (in terms of prices) for the users of these service providers.     

Determinants of motor vehicle crash fatalities using Bayesian model selection methods

Motor vehicle crashes continue to result in large numbers of fatalities each year and represent the leading cause of death for young persons. In 2006, for example, there were over 42,700 fatalities associated with these crashes. Understanding the causes of these crashes and methods to reduce them continues to be of great interest to economists, public health officials, and policy makers. We present in this paper statistical models using a rich set of panel data covering the period 1980 to 2007 by state and the District of Columbia. Our choice of variables is based on an extensive literature highlighting the importance of policy, safety, demographic, and economic determinants of fatality rates.