Steering short-term demand for car-sharing: a mode choice and policy impact analysis by trip distance

Transportation - Car-sharing could have substantial benefits. However, there is not enough evidence about if more people choosing car-sharing would reduce private car usage or public transport...     

The Gothenburg congestion charges: cost–benefit analysis and distribution effects

This paper performs an ex-post cost–benefit and distribution analysis of the Gothenburg congestion charges introduced in 2013, based on observed effects and an ex-post evaluated transport model. Although Gothenburg is a small city with congestion limited to the highway junctions, the congestion charge scheme is socially beneficial, generating a net surplus of €20 million per year. From a financial perspective, the investment cost was repaid in slightly more than a year and, from a social surplus perspective, is repaid in < 4 years. Still, the sums that are redistributed in Gothenburg are substantially larger than the net benefit. In the distribution analysis we develop an alternative welfare rule, where the utility is translated to money by dividing the utility by the average marginal utility of money, thereby avoiding putting a higher weight on high-income people. The alternative welfare rule shows larger re-distribution effects, because paying charges is more painful for low-income classes due to the higher marginal utility of money. Low-income citizens pay a larger share of their income because all income classes are highly car dependent in Gothenburg and workers in the highest income class have considerably higher access to company cars for private trips. No correlation was found between voting pattern and gains, losses or net gain.

     

TNFα、Leptin-Rb、NF-κB和PPAR-γ在酒精性肝病大鼠肝细胞中的表达

目的 探讨TNFα、NF-κB、Leptin-Rb和PPAR-γ等在大鼠酒精性肝病中与肝组织炎症、坏死和纤维化的关系.方法 胃造瘘法建立长期大鼠酒精性肝病模型,分别在第4、8、12、24和52周用免疫组化、原位杂交和RT-PCR技术检测不同阶段大鼠肝组织中TNFα、NF-κB、PPAR-γ和Leptin-Rb等的表达.结果 TNFα、NF-κB和Leptin-Rb水平在模型组大鼠肝细胞中,第8周表达逐渐增强,第24周起高水平表达一直持续至52周(P<0.01).PPAR-γ在对照组和第4、8周模型组肝细胞中表达最强,第12周表达开始减弱.TNFα和NF-κB在肝细胞中的表达呈明显正相关关系,与PPAR-γ则呈负相关关系(P<0.01).结论 TNFα和NF-κB与肝细胞病变程度有很好的一致性关系,Leptin-Rb在肝细胞的表达与肝纤维化发展相一致,PPAR-γ则刚好相反.     

体外大鼠成骨细胞对破骨细胞形成的影响

目的通过将鼠成骨细胞与破骨细胞直接共培养的实验方法,研究成骨细胞对破骨细胞分化及功能成熟的影响。方法按照M-CSF 30μg/L、RANKL 50μg/L的浓度对鼠骨髓单个核细胞诱导培养6 d,与原代培养3 d的鼠成骨细胞按细胞数量1∶1直接共培养,加入1,25-(OH)2D31×10-8mol/L和PGE21×10-6mol/L,利用形态学观察、TRAP染色、骨吸收陷窝检测等方法对共培养细胞进行鉴定。结果成骨细胞与破骨细胞共培养时,成骨细胞有明显的生长优势;染色后显微镜下可见大量呈单层排列的成骨细胞,偶见TRAP( )的破骨细胞。结论成骨细胞对破骨细胞分化及功能成熟的影响与两者的相对数量有关。本实验中,由于成骨细胞快速生长,当其数量多于破骨细胞时,可能使1,25-(OH)2D3对成骨细胞RANKL表达的上调作用不足,且PGE2对成骨细胞OPG表达的下调作用不足,从而主要表现为对破骨细胞形成及分化的抑制作用。     

An integrated framework for embedding large-scale dynamic traffic assignment models in advanced traveler information systems

In recent years, increasing attention has been drawn to the development of various applications of intelligent transportation systems (ITS), which are credited with the amelioration of traffic conditions in urban and regional environments. Advanced traveler information systems (ATIS) constitute an important element of ITS by providing potential travelers with information on the network's current performance both en-route and pre-trip. In order to tackle the complexity of such systems, derived from the difficulty of providing real-time estimations of current as well as forecasts of future traffic conditions, a series of models and algorithms have been initiated. This paper proposes the development of an integrated framework for real-time ATIS and presents its application on a large-scale network, that of Thessaloniki, Greece, concluding with a discussion on development and implementation challenges as well as on the advantages and limitations of such an effort.     

浅谈滚动物料计划在汽车行业中的应用

随着汽车逐年普及,消费者需求多样化、个性化随着增长,而且消费者对提车周期要求越来越高.汽车生产企业如何快速、高效的占领市场,同时降低供应链物流成本,是目前自主品牌汽车企业面临重大挑战.需要从软硬件进行全面提升竞争能力,物料组织改进是整个汽车供应链改进不可缺少的一个重要环节,能帮助企业迅速占领市场,以最小的成本换取最大利...     

On the income elasticity of the value of travel time

Transport infrastructure is long-term and in appraisal it is necessary to value travel time savings for future years. This requires knowing how the value of time (VTT) will develop over time as incomes grow. This paper investigates if the cross-sectional income elasticity of the VTT is equal to inter-temporal income elasticity. The study is based on two identical stated choice experiments conducted with a 13 year interval. Results indicate that the relationship between income and the VTT in the cross-section has remained unchanged over time. As a consequence, the inter-temporal income elasticity of the VTT can be predicted based on cross-sectional income elasticity. However, the income elasticity of the VTT is not a constant but increases with income. For this reason, the average income elasticity of the VTT in the cross-sections has increased between the two survey years and can be expected to increase further over time.     

In situ colonization of marine biofilms on UNS S32760 duplex stainless steel coupons in areas with different water qualities: Implications for corrosion potential behavior

In the presence of biofilms, stainless steels （SS） exhibits an increase in corrosion potential, called ennoblement. In the present study, the corrosion potential （Eco,） behavior of the duplex SS UNS S32760 was recorded simultaneously with the in situ marine biofilm formation in two areas at Arraial do Cabo, Southeastern Brazil. The biofilm at Forno Harbor （an anthropogenically disturbed area） was characterized by higher relative abundances of Bacteria at day 2, followed by diatoms （especially Navicula sp.） on day 10 and dinoflagellates on day 18, whereas no clear trend was recorded at Cabo Frio Island （an undisturbed area）. The ennoblement of Ecor values was site-dependent. In a complementary laboratory assay, biofilms were removed and the Eco values registered in sterile conditions for the subsequent 10 days and corroborated in situ results. Understanding biofilms and SS interactions has important implications for materials science and engineering decisions as well as helping to fill in imnortant gaps in this knowledge.     

AMP眼光独到欲辟新天地

去年，前游泳国手Mark Young伙同两名业内知名人士，创办了一家专门针对小众市场的航运公司-Asia Maritime Pacific（AMP），以期在一些较为冷门的亚洲区间航线大展身手。据这家设于香港的公司表示，这类航线经常被老牌公司所忽略。     

Service-oriented computing and model-driven development as enablers of port information systems: an integrated view

Port information management is considered a critical instrument towards enabling international transport and trade; thus, various forms of Port Information Systems (PORTIS) have been developed today, namely Port Community Systems, Terminal Operating Systems and Single Window systems. In Europe, the nautical information system SafeSeaNet is viewed as an important e-infrastructure. PORTIS systems are expected to evolve into next-generation technological platforms in order to offer a fully integrated digital environment to a multitude of maritime business actors and public authorities towards more efficient, safe and environment-aware transport and trade infrastructures and services. We propose service-oriented computing and model-driven development techniques as a robust PORTIS modelling and development approach. We present a reference model of PORTIS and a particular enabling methodological and technological framework. The proposed approach has been tested in a maritime single-window case.