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SinceIsaacsandLindenmanndescribedinterferon(IFN)asanaturallyoccurringantiviralsubstance,threeantigenicallydifferenttypesofIFN(IFN--Q,IFN5,andIFN--Y)havebeenidentified,andithasbeendemonstratedthattheyhavenotonlyantiviralfunction,butalsoantiproliferaitveandimmunomodulatoryactivities.RecombinantDNAtechnologynowpermitstheproductionofpurifiedhumanIFNs,andhasprovidedanopportunityforsystematicstudyoftheinvitroandinvivoeffectsofeachtypeofhumanrecombinantIFN(rIFN)ontumorcells.EachtypeofIFN… 相似文献
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