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本文以螯虾细小神经轴突为标本,成功地应用双玻璃微电极进行细胞内刺激与电活动的记录。观察了细小神经轴突膜电生理和物理特性参数。钾离子通道特异性阻滞剂4—氨基吡啶,使Weiss式中常数b值显著减少;a值无明显变化;膜静息电位去极化;阈电位水平上移;动作电位幅值、锋电位时程、膜电阻和膜时间常数均有显著意义的增加。结果提示:4—氨基吡啶可提高膜的应激性,对神经膜兴奋性无明显影响;生物膜应激性及膜电阻的变化与钾通道的活动状态有密切关系。 相似文献
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同步定位与地图构建(Simultaneous Location and Mapping, SLAM)是机器人在未知环境中实现自我导航能力的重要保证。目前SLAM算法使用的主传感器基本是激光雷达或视觉相机。二者各具优劣,激光雷达能更精确地进行测距,视觉相机能反映环境丰富的纹理信息。与使用单一传感器相比,将二者融合的SLAM算法能够获得更多环境信息,达到更好的定位和建图效果。文章提出一种融合激光雷达和视觉相机的帧间匹配方法,通过在SLAM帧间匹配过程中加入地面约束以及视觉特征约束,提高帧间匹配过程精度,增强算法鲁棒性,从而提升SLAM算法整体效果。文章最后利用采集的地下停车库数据进行结果验证,与开源算法A-LOAM进行对比。结果表明,相比A-LOAM的帧间匹配方法,文章提出的方法相对位姿误差提升约30%。 相似文献
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本实验应用豚鼠内耳母抗原液免疫豚鼠产生自身免疫性感音神经性耳聋(AISNHL),后用地塞米松治疗1周,并行听觉脑干诱发电位阈(ABRT)测定和内耳形态学观察。我们发现免疫后豚鼠ABRT升高到60.8±531dBSPL、耳蜗第3回外毛细胞损失达111.0±55.8个;而应用地塞米松治疗后的豚鼠ABRT则下降为48.8±6.69dBSPL。耳蜗第3回外毛细胞损失仅为57.25±18个,证实地塞米松对AISNHL有治疗效果,它可使内耳组织恢复,ABRT明显改善,其机制尚不明了。 相似文献
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本文观察了不同浓度(10~(-8)~10~(-4)mol/L)的亚硒酸钠、硒酸钠和硒蛋氨酸对体外培养淋巴细胞DNA、RNA和蛋白质合成,ATP含量及GSH—px活性的影响,以比较3种硒化合物的毒性。结果表明3种硒化合物对DNA、RNA和蛋白质合成均有双相效应,在10~(-4)mol/L时亚硒酸钠抑制率高于硒酸钠和硒蛋氨酸(P<0.0001),ATP含量随硒浓度增加明显低于对照组。3种化合物的毒性顺序为:亚硒酸钠>硒酸钠>硒蛋氨酸。在实验浓度范围内GSH—px活性均高于对照组。 相似文献
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The flight perturbation problem 总被引:1,自引:0,他引:1
T. Andersson 《运输规划与技术》2013,36(2):91-117
Airlines spend considerable time, effort and financial resources on planning. It is essential to create a competitive timetable and construct a fleet and a crew schedule that utilizes these resources to the maximum. Unfortunately, it is all too common that an airline is faced with the necessity of reconstructing their schedules due to some unforeseen event, for example an aircraft breakdown or a crew member that is indisposed. In this paper, an application that can help airlines solve the complex problem of reconstructing aircraft schedules is presented. A mixed integer multicommodity flow model with side constraints is developed and further reformulated into a set packing model using the Dantzig—Wolfe decomposition. Cancellations, delays and aircraft swaps are used to resolve the perturbation, and the model ensures that the schedule returns to normal within a certain time. Two column generation schemes for heuristically solving the model are tested on real problem data obtained from a Swedish domestic airline. The computational tests show that the application is capable of presenting high quality solutions in a few seconds and therefore can be used as a dynamic decision support tool by the airlines. 相似文献
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