Changing accessibility, dwelling price and the spatial distribution of socio-economic activities

In this paper we present an activities-location choice model with endogenous price which simulates, based on Expected Random Utility principle, the behaviour of several agents of the urban system (e.g. the workers distinguished by income, the firms by economic sector) to estimate the spatial distribution of socio-economic activities within the study area as well as the impact of differential changes in accessibility on the dwelling price. The study area for this research is the metropolitan area of Napoli (South Italy), for which we show the results of the model estimation and the results of a “backcasting” analysis.     

An activity-episode generation model that captures interactions between household heads: development and empirical analysis

In this paper, we develop an approach for modeling the daily number of non-work, out-of-home activity episodes for household heads that incorporates in its framework both interactions between such members and activity setting (i.e. independent and joint activities). Trivariate ordered probit models are estimated for the heads of three household types – couple, non-worker; couple, one-worker; and couple, two-worker households – using data from a trip diary survey that was conducted in the Greater Toronto Area (GTA) during 1987. Significant interactions between household heads are found. Moreover, the nature of these interactions is shown to vary by household type implying that decision-making structures and, more generally, household dynamics also vary by household type. In terms of predictive ability, the models incorporating interactions are found to predict more accurately than models excluding interactions. The empirical findings emphasize the importance of incorporating interactions between household members in activity-based forecasting models.     

Screening of chemokine receptor CCR4 antagonists by capillary zone electrophoresis

Abstract CC chemokine receptor 4 （CCR4） is a kind of G-protein-coupled receptor, which plays a pivotal role in allergic inflammation. The interaction between 2-（2-（4-chloro-phenyl）-5-{[（naphthalen-1- y...