Measurement and correlation of the solubility of 1-hydroxyphenazine in different solvents at temperature from 278.5 to 333.5K

Compound of 1-hydroxyphenazine (1-OH-PHZ) is an important fungicide in agricultural production. The ranges of 1-OH-PHZ solubilities in dichloromethane at temperature of 278.5–308.5 K and in ethyl acetate, methanol and water at temperature of 278.5–333.5 K were measured using the analytical stirred flask method at barometric pressure. The color of the liquid remained unchanged throughout. The solubilities of 1-OH-PHZ in water, methanol, ethyl acetate and dichloromethane increased orderly and these solubilities also increased with increasing the temperature. The experimental data was correlated by the modified Apelblat equation. The root mean square deviations were all within 0.5% and the maximum relative average deviation was 5.2%. The calculated solubility shows a good relationship with the experimental solubility.