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Jerne'spredictionthatanti--idantibodiescaninduceimmunitytonominalantigens','hasbeenshowninanumberofantigenicsystems,includingseveralhumantumor-associatedantigensystems',~.'.Antitumor-associatedantigenimmunityelicitedbyanti--idantibodieshasbeenshowntohaveabeneficialeffectonthecourseofmalignancyinanimalmodelsystems.Furthermore,werecentlyhavefoundthatthemouseanti--idmAbMK2--23whichbearstheinternalimageofhumanhighmolecularweightmelanoma--associatedantigen(HMW-MAA)'caninduceanti--HMWMAAimmuni… 相似文献
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