狗左右心室和肺循环功能的同步测定与评价

本文介绍了狗左、右心室和肺循环功能的同步测定方法,并同时观察了左、右心室收缩、舒张性能、泵功能和肺循环功能的多项指标。在实验条件下,动物的生理状况在3小时内基本稳定。     

平交路口远引掉头设置方法分析

平交路口远引是解决路口流向禁限后车流转向问题的有效方法。通过对掉头地点的选址规划以及交叉口之间的协调控制进行研究,提出最佳掉头位置应满足的条件以及交叉口协调控制的相位差计算方法。通过对掉头通道通行能力的分析,提出实施掉头信号控制条件和具体实施方法。     

二尖瓣脱垂综合征患者QT离散度分析

测定了30例二尖瓣脱垂综合征伴室性心律失常患者的QTd。结果发现，二尖瓣脱垂组QTd、QTcd、JTd显著延长，说明心室肌复极有局部的不均一性和电不稳定性，离散度与室性心律失常的发生密切相关，可能是室性心律失常发生的机理之一。QTd不仅能预测室性心律失常及猝死，而且能指导临床用药，是一很好的临床观察指标。     

Safety modeling for two‐way left‐turn lanes and a procedure to identify two‐way left‐turn lane segments with safety concerns

In the past, two‐way left‐turn lane (TWLTL) median treatments have been frequently used in Florida to inexpensively improve traffic and safety performances. In order to identify factors that may have significant impacts on safety operations in TWLTL sections and to identify TWLTL locations that present existing and future safety concerns, a research project was carried out and results are summarized in the paper. In the research, a three‐year crash history database with crashes and section characteristics from a total of 1688 TWLTL sections all over Florida was developed and used. A negative binomial regression model was developed to determine the statistical relationship between the number of crashes per mile per year and several variables such as traffic volume, access density, posted speed, and number of lanes. In regard to the methodology, in order to identify locations with safety concerns, several steps are needed: development of real crash data distribution, determination of statistical distribution models that better represent the actual crash data, determination of percentile values for the average number of crashes, estimation of crash rates for sections with the same characteristics, estimation of critical values for the variables corresponding to the percentile values for average number of crashes, calculation of tables of critical average annual daily traffic values, and generation of a list of TWLTL locations with critical safety concerns. Results presented in the paper have been used in real applications. Copyright © 2012 John Wiley & Sons, Ltd.     

ELECTROPHYSIOLOGICAL EFFECTS OF TETRAHYDROPALMATINE ON CANINE PURKINJE FIBER AND VENTRICULAR MUSCLE IN VITRO

ＥＬＥＣＴＲＯＰＨＹＳＩＯＬＯＧＩＣＡＬＥＦＦＥＣＴＳＯＦＴＥＴＲＡＨＹＤＲＯＰＡＬＭＡＴＩＮＥＯＮＣＡＮＩＮＥＰＵＲＫＩＮＪＥＦＩＢＥＲＡＮＤＶＥＮＴＲＩＣＵＬＡＲ　ＭＵＳＣＬＥＩＮＶＩＴＲＯＺｈａｎｇＤｉａｎｚｅｎｇ（张殿增）；ＬｉＸｉｋｕａｎ（...     

平面交叉口港湾式左转车道安全设计

在平面交叉口交通事故中,与左转相关的事故占较大比例,而设置港湾式左转车道,可有效改善平交路口的交通安全状况。分析左转车辆对交叉口安全性的影响,确定设置港湾式左转车道的主要因素,并结合国内外研究,从左转车道的长度和宽度等方面对左转车道的设计进行探讨,提出平面交叉口港湾式左转车道的安全设计方法并分析其安全效益。     

大鼠容量超负荷性心肌肥厚时cAMP、cGMP对机械信号刺激的应答反应

目的　动态观察大鼠容量超负荷性心肌肥厚模型中环磷酸腺苷 (cAMP)、环磷酸鸟苷(cGMP)对机械信号刺激的应答反应。方法　应用放射免疫方法观察在容量负荷后不同时间点大鼠心肌中cAMP、cGMP的变化以及在慢性容量超负荷基础上给予急性容量负荷时cAMP、cGMP对机械信号刺激的应答反应。结果　容量负荷后即刻及 4～ 6h ,cAMP、cGMP均明显下降 ,其后逐渐上升 ,1周时cAMP超过正常水平 ,cGMP超过手术对照组水平 ,2周后cAMP、cGMP均下降 ,5个月时显著下降 ;在慢性容量超负荷基础上给予急性容量负荷时心功能恶化 ,同时cAMP呈现反常反应。结论　cAMP、cGMP对机械信号刺激的应答反应表明肥厚心肌存在机械信号跨膜传递障碍。研究这种障碍需进一步探索机械信号跨膜传递通路是由那些环节组成及如何相互作用参与机械信号跨膜传递。     

室间隔缺损并肺动脉高压102例外科治疗

先天性心脏病室间隔缺损（ＶＳＤ）是一常见多发病，由于存在左向右分流，常导致肺动脉高压（ＰＨ），使围手术期死亡率增加，预后不佳，故早期发现、早期手术治疗己被重视。本文对１０２例ＶＳＤ·ＰＨ患者外科手术治疗进行分析，并对手术适应症、手术径路、并发症预防及术后处理进行讨论。     

超声测量技术在心血管机能研究中的应用与评价

本文扼要介绍了超声测量技术的原理、方法及其应用。与急性实验比较,它具有不受麻醉、损伤的影响,动物处于生理状态下,仪器灵敏度较高,数据较精确,可同步记录室壁收缩状态与心功能各参数的变化,便于作精确的相关分析等优点。适于生理、药理及病理生理学心血管机能的慢性实验研究。     

Modeling traffic operation at signalized intersections without explicit left‐turn yielding rules with an enhanced cell transmission model

This paper presents an enhanced cell transmission model (CTM) to capture traffic operation at signalized intersections without explicit permissive left‐turn yielding rules (i.e. aggressive permissive left‐turn maneuvers may not necessarily yield to opposing through traffic), which can be widely observed in many developing countries. Different from previous studies that focus on traffic dynamics on approaching links, this study contributes to modeling traffic operations within the intersection. A novel cell transmission framework with various types of virtual cells is proposed to model the dynamics of traffic movements from approach to exit. The unique phenomenon of competitive occupying of the conflict point between the left turn and opposing through movements is modeled. The cell state indicating its blockage is proposed to capture the dynamic queue formulation and dissipation and to evaluate the operational traffic performance at the intersection. Field validation results show that the proposed model can capture the operation of traffic at signalized intersections without explicit permissive left‐turn yielding rules with significantly higher level of accuracy than traditional traffic flow models. Copyright © 2016 John Wiley & Sons, Ltd.