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Studies on the carcinomas showed thattumori-genesis was critically related to the acceleration ofcell proliferation and disturbance of apoptosis.Ab-normal cell cycle might lead to uncontrolled cellproliferation and promote oncogenesis.P2 1 is awide- spectrum cyclin- dependent kinase inhibitorand negatively control cell cycle progression.Chen[1] found thatover- expression of P2 1 can inhibittu-mor growth.Cyclin D1 is a regulatory protein thatcontrol cell cycle transit from G1 into S phase.… 相似文献
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