Establishment of Community Managed Fisheries’ Closures in Kenya: Early Evolution of the Tengefu Movement

Community-based management (CBM) could be an essential tool to prevent the depletion of marine resources in the Western Indian Ocean region. In Kenya, political pressure to strengthen local governance, has led to adoption of CBM as a way of reducing over-exploitation and managing the competing uses and impacts on the marine environment. Several communities in Kenya have embraced CBM and have set aside or closed previously fished areas to enhance recovery of fisheries and biodiversity. These community fisheries closures (locally called tengefu), despite being degraded, may recover to finfish abundances and biodiversity levels similar to established MPAs or above thresholds for maintaining some ecological services. Communities see their direct involvement and control of these tengefu as more likely to result in benefits flowing directly to them. Community closures are also important for articulating and resolving community values and strengthening their management capacity. Here, we describe the evolution of the tengefu movement in Kenya and combine information from focus group discussions, interviews, underwater surveys and boundary marking to evaluate the current status, opportunities and challenges facing these tengefu. We show that in some cases community closures suffer from slow and incomplete national and local legislative processes, challenges to compliance, and weak management.     

羟基喜树碱对人胆管癌QBC939裸鼠移植瘤PS2、COX-2的影响

目的探讨羟基喜树碱对人胆管癌QBC939裸鼠移植瘤的乳癌相关肽(PS2)、环氧合酶-2(COX-2)的影响,分析PS2、COX-2与肿瘤发生、发展的关系。方法建立人胆管癌QBC939细胞株裸鼠皮下移植瘤模型,将30只裸鼠随机分成对照组、羟基喜树碱低剂量组和羟基喜树碱高剂量组,观察移植瘤体生长情况,RT-PCR法检测瘤体内PS2、COX-2 mRNA表达。结果与对照组比,羟基喜树碱低、高剂量组都可使移植瘤体的PS2 mRNA表达增高;COX-2 mRNA表达降低,且瘤体生长减慢,与对照组比较差异有统计学意义(P<0.01)。结论羟基喜树碱可降低移植瘤COX-2 mRNA表达,增高移植瘤体的PS2 mRNA表达,并使人胆管癌裸鼠移植瘤生长减慢。     

彩色多普勒超声在动态监测移植肝及其并发症中的应用

目的探讨彩色多普勒超声在动态监测肝移植术后血流动力学变化及并发症诊治中的应用价值。方法回顾我中心107例原位肝移植术后应用彩色多普勒超声资料,汇总后行统计学分析。结果肝移植术后早期门脉流速较正常对照组升高,而肝动脉流速降低,后逐渐恢复正常。107例中发现肝动脉血栓形成2例(1.87%),肝动脉狭窄5例(4.67%),门脉血栓形成3例(2.80%),肿瘤复发7例(6.54%),诊断为急性排斥反应18例次(16.82%),慢性排斥反应10例次(9.34%),胸腔积液105例(98.13%),腹腔积液65例(60.74%),假性动脉瘤1例,胰漏1例,胆道感染4例(3.74%),胆道狭窄4例(3.74%),胆漏5例(4.67%),胆总管结石1例。结论彩色多普勒超声在动态监测肝移植术后血流动力学变化及并发症诊治中具有重要的临床意义。     

西沙群岛珊瑚砂运动特性试验研究

珊瑚砂具有颗粒密度较大、孔隙率较高、干密度较小、压缩性较高等物理特性。其形成过程相对短暂,搬运距离有限,珊瑚砂磨圆度较低,颗粒形态差异明显,颗粒之间有效接触面积较小,粘着力较低。这些特性决定了珊瑚砂在动力作用下易于起动搬运的运动特征。文章对西沙群岛珊瑚砂的比重、孔隙率、休止角和渗透性等物理性质以及水流、波浪作用下的起动特性进行了试验测定,试验结果也表明了珊瑚砂起动特性符合目前经验公式计算值。     

A Training Framework for Understanding Conflict in the Coastal Zone

The coastal zone is attractive for human settlement because it tends to be resource rich, providing a good location to generate incomes and livelihoods. Equally, however, it is a complex and powerful natural environment, which means that the coastal zone often becomes a focus of conflict with multiple users competing for limited space and resources. Understanding the causes of, and determining solutions to, the ensuing problems requires inputs from a range of analyses across sectors and disciplines. However, different disciplinary and sectoral approaches frequently use different investigative methods, language, and means of presenting results. This article presents a framework that has been developed in collaboration with Indian institutions over the past three years in an effort to address some of these fundamental problems of analysis and translation into policy action. Key components addressed by the framework are strengthening the capacity to practice, knowing how to proceed and how to find out what needs to be known using experience-based problem solving.     

Monitoring Human Activity in an Area Dedicated to the Protection of the Endangered Mediterranean Monk Seal

Mediterranean monk seal populations have declined dramatically and survive in subpopulations scattered throughout their original distribution. The National Marine Park of Alonnisos, Northern Sporades is the first marine protected Area dedicated to the protection of the species in the Mediterranean. A Monitoring and Awareness Project has been carried out in the area from 1993 to 2000, the results of which have produced a detailed profile of the human usage pattern of the Park and indicated a significant reduction of illegal activities in the area. The pattern of human usage has enabled the monitoring team to adjust their efforts in the Park over time and provided essential baseline data for future management. The combined monitoring and awareness efforts have contributed significantly to the conservation of the Mediterranean monk seal by successfully protecting pupping sites and reducing human-induced mortality of the species in the area.     

珊瑚礁灰岩可搅拌性PFC3D数值模拟研究

利用珊瑚礁灰岩地区某工程的三轴搅拌桩施工现场数据,采用PFC~(3D)离散元软件分别对不同珊瑚礁灰岩强度、厚度,以及上覆土层厚度进行数值模拟分析。模拟结果显示,当珊瑚礁灰岩强度超过4 MPa,厚度超过3 m后,三轴搅拌机竖向抗力及抵抗弯矩达到其自身性能的极限,出现卡钻、抱钻情况,从而造成三轴搅拌桩止水帷幕无法施工,而上覆土层厚度的变化则对施工几乎没有影响。用离散元模拟结果与现场实际施工情况进行比较发现:数值模拟结果与现场实际施工情况较为吻合,对现场施工有一定的指导作用。     

肯尼亚拉姆港疏浚工程施工工艺优化

肯尼亚拉姆港疏浚及吹填工程土质以珊瑚质石灰岩混黏土为主。针对绞吸船在施工时易堵口堵泵、硬质珊瑚岩易造成绞刀损坏并严重影响船舶正常施工等问题,对绞刀的型号、防石装置及挖掘工艺进行研究。采用理论分析与现场试验相结合的方式,对绞刀和刀齿进行强度改造,有效提高生产效率;同时安装拨石碎石装置,防石效果较好;时间利用率达到75%以上,在节约施工成本的同时缩短了工期。     

恶性血液病患者自体骨髓移植的临床研究

采用VCAD±DE／F－TBI方案预处理，移植经微波高温42℃1h净化的自体骨髓1.6×108MNC／kg，含GM－CFU5.7×104/kg，全环境保护，治疗急性白血病（AL）8例，非何杰金淋巴瘤（NHL）2例。结果：9例植活，3年无病生存率9／10例，无重要并发症及复发，移植半年后恢复工作。     

巨细胞病毒感染诱导移植排斥反应的机制研究

目的以人脐静脉内皮细胞(HUVECs)ECV304株作为研究对象,探讨巨细胞病毒(CMV)感染诱发排斥反应的机制。方法体外培养ECV304,施加不同干预因素,分为正常对照组、灭活病毒作用组、病毒作用组、病毒上清液作用组及病毒与更昔洛韦组。运用免疫组化技术检测不同组别内皮细胞表面细胞间粘附分子-1(ICAM-1)的表达。结果正常对照组内皮细胞ICAM-1的表达呈弱阳性,加入灭活的病毒及病毒上清液后,ICAM-1的表达仍为弱阳性(P>0.05);加入有活力的病毒后,内皮细胞ICAM-1的表达呈强阳性,积分指数显著高于上述3组(P<0.01);在CMV感染内皮细胞的同时加入更昔洛韦,细胞表面ICAM-1表达强度较病毒组并无减低(P>0.05)。结论CMV感染的内皮细胞表面ICAM-1的表达明显增加。通过诱导内皮细胞表面ICAM-1表达上调可能是CMV诱发排斥反应的机制之一。