| HA方案治疗慢性粒细胞白血病23例疗效观察 |
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| 引用本文： | 乔义超,陈银霞,田国栋,叶民刚. HA方案治疗慢性粒细胞白血病23例疗效观察[J]. 西安交通大学学报(医学版), 1993, 0(2) |
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| 作者姓名： | 乔义超 陈银霞 田国栋 叶民刚 |
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| 作者单位： | 西安医科大学第二附属医院血液科，西安医科大学第二附属医院血液科，西安医科大学第二附属医院血液科，西安医科大学第二附属医院血液科 西安 710004，西安 710004，西安 710004，西安 710004 |
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| 摘 要： | 用HA方案(H:三尖杉酯碱,A:阿糖胞苷)治疗23例慢性粒细胞白血病(CML),完全缓解13例,部分缓解10例,与马利兰治疗组相比,白细胞开始下降及降至<10.0×10~9/L(马利兰组降至<20.0×10~9/L)所需时间,脾脏开始回缩及缩至最小所需时间,自觉症状的改善均较优。对缓解后再复发及缓解后的维持治疗也敏感有效。维持治疗的时间选择及间隔时间应个体化。
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| 关 键 词： | 慢性粒细胞白血病 HA方案 治疗 缓解 |
OBSERVATION OF CURATIVE EFFECT OF HA IN 23 CASES WITH CML |
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| Qiao Yichao,Chen Yinxia,Tian Goudong. OBSERVATION OF CURATIVE EFFECT OF HA IN 23 CASES WITH CML[J]. Journal of Xi‘an Jiaotong University:Medical Sciences, 1993, 0(2) |
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| Authors: | Qiao Yichao Chen Yinxia Tian Goudong |
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| Affiliation: | Qiao Yichao,Chen Yinxia,Tian Goudong Department of Hematology,Second Affiliated Hospital |
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| Abstract: | The 23 cases with chronic myelogenousleukemia (CML) were treated with program ofharringtonine and ara-c (HA) and the results werethat the 13 cases got complete remission and 10cases got partial remission. Comparing with thecontrol group the patients of which were treatedwith busulfan, the authors found that the spendedtime of decreased WBC in blood (WBC decreasedto 10. 0 × 10~9/L) and reduced spleen (reduced tosmallest status of spleen) and improvement of self-sensation symptoms in the group treated with HAwere better than those in control group. The HAprogram for cases who recured CML again and re-ceived maintenance cure after remission of CMLwas still effective. The time of maintenance cureand interval should be individualized. |
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| Keywords: | chronic myelogenous leukemia HA program treatmint remission |
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