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THE GENE EXPRESSION OF BDNF IN NORMAL RABBIT RETINA
作者姓名:王建明  胡海涛  马东亮  孙乃学  赵世平  冯海晓
作者单位:[1]DepartmentofOphthalmology,SecondHospitalofXi'anJiaotongUniversity,Xi'an710004,China [2]不详,SecondHospitalofXi'anJiaotongUniversity,Xi'an710004,China [3]DepartmentofOphthalmology,SecondHospitalofXi'anJiaotongUniversity,Xi'an710004,China
基金项目:ThisstudywassupportedbytheNaturalScienceFoundationofShaanxiProvince,China(No.2001SM66).
摘    要:Objective To investigate the distribution of brain-derived neurotrophic factor(BDNF) protein in the rabbit retina. Methods Immune response material in the retina was observed using BDNF antibody by the method of immunohistochemistry. Results BDNF gene expression was mainly found in the RGCs, also in innernuclei cells and outernuclei cells in rabbit retina. Conclusion RGC is not only the target cell of BDNF, but also express the BDNF protein. BDNF from multi-sources participates in the regulation of RGCs.

关 键 词:BDNF  基因表达  神经节细胞  视网膜

THE GENE EXPRESSION OF BDNF IN NORMAL RABBIT RETINA
Wang Jianming,Hu Haitao ,Ma Dongliang ,Sun Naixue,Zhao Shiping,Feng Haixiao.THE GENE EXPRESSION OF BDNF IN NORMAL RABBIT RETINA[J].Academic Journal of Xi’an Jiaotong University,2004,16(2):188-189,192.
Authors:Wang Jianming  Hu Haitao  Ma Dongliang  Sun Naixue  Zhao Shiping  Feng Haixiao
Institution:1. Department of Ophthalmology, Second Hospital of Xi'an Jiaotong University, Xi'an 710004, China.
2. Department of Human Anatomy, Medical School of Xi'an Jiaotong University, Xi'an 710061, China.
Abstract:Objective To investigate the distribution of bra in-derived neurotrophic factor(BDNF) protein in the rabbit retina. Methods Immune response material in the retina was observed using BDNF antibody by the method of immunohistochemistry. Results BDNF gene expression was mainly found in the RGCs, a lso in innernuclei cells and outernuclei cells in rabbit retina. Conclusion RGC is not only the target cell of BDNF, but also express the BDNF protein. BDNF from multi-sources participates in the regulati on of RGCs.
Keywords:brain-derived neurotrophic factor(BDNF)  gene exp ression  retina ganglion cell
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