| 饲低硒粮大鼠线粒体膜结合酶活力的变化 |
| |
| 引用本文： | 韩锋产,袁素芬.饲低硒粮大鼠线粒体膜结合酶活力的变化[J].西安交通大学学报(医学版),1992(4). |
| |
| 作者姓名： | 韩锋产 袁素芬 |
| |
| 作者单位： | 西安医科大学生物化学教研室，西安医科大学生物化学教研室 西安 710061咸阳市第二人民医院内科，西安 710061 |
| |
| 摘 要： | 本文采用大骨节病区低硒粮饲养大鼠3～5个月,观察其骨骼肌、心肌线粒体SDH、H~+-ATP_(ase)与CKm 3种酶活力的变化。结果表明:饲低硒粮3个月或5个月之大鼠线粒体此3种膜结合酶活力均明显降低;给大鼠补充亚硒酸盐后,可使此3种酶活力升高,但仍未达到西安粮组的水平。这些结果提示,长期饲以低硒粮的大鼠可引起能量代谢障碍。
|
| 关 键 词： | 大骨节病 线粒体 肌酸激酶 琥珀酸脱氢酶 H~+-ATP酶 硒 |
CHANGES OF ACTIVITIES OF MITOCHONDRIAL MEMBRANE BINDING ENZYMES IN RATS FED WITH LOW—Se DIET |
| |
| Han Fengchan,Yuan Sufen.CHANGES OF ACTIVITIES OF MITOCHONDRIAL MEMBRANE BINDING ENZYMES IN RATS FED WITH LOW—Se DIET[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1992(4). |
| |
| Authors: | Han Fengchan Yuan Sufen |
| |
| Institution: | Department of Biochemistry |
| |
| Abstract: | In this article the activities of succinic dehydrogenase, H~+ -ATPase and creatine kinase in skeletal muscle and heart mitochondria of rats fed with low-Se diet from kashin-beck disease area for 3 to 5 months were observed. The experiments showed that the activities of these three membrane binding enzymes were decreased significantly in mitochondria of rats fed with low-Se diet for 3 to 5 months, as compared to rats suplemented with sodium selenite, but still had not reached the levels in rats fed with diet from Xi'an area.
These results suggested that the disturbance of energy metabolism may be induced when the rats fed with low-Se diet for long term. |
| |
| Keywords: | kashin-bech disease mitochondria creatine kinase suceinic dehydrogenase proton—translocating adrenosine triphosphatasel selenium |
| 本文献已被 CNKI 等数据库收录！ |
