| 铅和脂质过氧化作用 |
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| 引用本文： | 廖东铭,朱夏燕,姜岳明.铅和脂质过氧化作用[J].铁道劳动安全卫生与环保,2006,33(4):208-211. |
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| 作者姓名： | 廖东铭 朱夏燕 姜岳明 |
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| 作者单位： | 1. 广西宜州市疾病预防控制中心,广西,宜州,546300
2. 广西医科大学劳动卫生学与毒理学教研室,广西,南宁,530021 |
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| 摘 要： | 人接触铅的机会很多,无论是职业性接触还是环境低浓度接触,都可引起铅吸收和铅蓄积,并通过一系列生化反应,造成血液、肝、肾和脑等多种靶器官的损害。生物膜是铅毒作用的敏感部位之一。铅可能通过脂质过氧化(LPO)反应导致膜变性及其功能障碍,并产生丙二醛(MDA),以至对机体引起有害的影响。
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| 关 键 词： | 铅 |
| 文章编号： | 1003-1197(2006)04-0208-04 |
| 收稿时间： | 2006-06-10 |
| 修稿时间： | 2006年6月10日 |
Lead and Lipid Peroxidation |
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| LIAO Dong-ming,ZHU Xia-yan,JIANG Yue-ming.Lead and Lipid Peroxidation[J].Railway Occupational Safety Health & Environmental Protection,2006,33(4):208-211. |
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| Authors: | LIAO Dong-ming ZHU Xia-yan JIANG Yue-ming |
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| Institution: | 1. Guangxi Yizhou Centers for Diseases Control and Prevention , Yizbou 546300, China ; 2. Dept of Occupational Health and Toxicology, Guangxi Medical University, Nanning 530021 , China |
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| Abstract: | There are many opportunities for people to be exposed to lead.Occupational and low-level environmental lead exposure can cause its absorption and accumulation in the body.Then target organism or system such as blood,liver,kidney and brain are damaged by a series of biochemical events.Biological membranes may be one of the more sensitive systems to lead poisoning action.The degeneration and dysfunction of the membrane are possibly induced via lipid peroxidation,which produce malonaldehyde which causes humen to be affected. |
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| Keywords: | LPO MDA SOD |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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