补硒对大鼠胰腺活体内蛋白质合成的影响

断奶１周的大鼠分为３组，分别饲与克山病病区低硒粮饲料（硒含量０．００９ｍｇ／ｋｇ）和基础饲料补加不同量亚硒酸钠（补硒量０．１ｍｇ／ｋｇ或０．４ｍｇ／ｋｇ）以探讨硒对大鼠胰腺活体内蛋白质合成的影响。结果表明：补硒（０．１ｍｇ／ｋｇ或０．４ｍｇ／ｋｇ）与未补硒大鼠比较，补硒大鼠的胰腺（３Ｈ）－亮氨酸参入活性、蛋白质和ＲＮＡ含量都显著增加。在同样的补硒水平，肝的硒含量和ＧＳＨ－Ｐｘ活性也显示明显增高。

EFFECT OF SELENIUM SUPPLEMENTATION ON IN VIVO PROTEIN SYNTHESIS IN PANCREAS OF RATS

To investigate the effect of selenium (Se) supplementation on pancreatic protein synthesis in vivo,three groups of weaning rats were fed on a low-selenium diet composed of grains from a Keshan disease area (containing 0.009mg/kg Se) or the basal diet supplemented with two levels of selenium as sodium selenite (0.1 or 0.4mg Se/kg diet),respectively. The results showed that with sodium selenite supplementation at level of either 0.1 mg/kg or 0. 4mg/kg Se, the amino acid incorporation activity, amounts of protein and RNA all increased significantly in pancreas of the Se-supplemented rats, when compared to the unsupplemented rats,significant increases in the Se content and GSH-Px activity in liver were also observed.