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亚硒酸钠对离体蟾蜍脊髓背根电位的影响
引用本文:赵放理,梅俊.亚硒酸钠对离体蟾蜍脊髓背根电位的影响[J].西安交通大学学报(医学版),1990(1).
作者姓名:赵放理  梅俊
作者单位:西安医科大学脑和神经研究室 (赵放理),西安医科大学脑和神经研究室(梅俊)
摘    要:本文观察亚硒竣钠对离体蟾蜍脊髓背根电位的作用。结果表明:亚硒酸钠对背根电位(DR-DRP、VR-DRP)的幅度呈现先增高后降低的双相效应。用蔗糖间隙法记录证明亚硒酸钠对背根有去极化作用。通过进一步的实验分析认为:亚硒酸钠所诱发的自发性背根电位是其对中间神经元活动影响的结果。并结合有关资料对亚硒酸钠的作用机制作了初步探讨。

关 键 词:亚硒酸钠  背根电位  去极化  自发性背根电位

THE EFFECT OF SODIUM SELENITE ON DORSAL ROOT POTENTIALS IN ISOLATED SPINAL CORD OF THE TOAD
Zhao Fangli Mei Jun.THE EFFECT OF SODIUM SELENITE ON DORSAL ROOT POTENTIALS IN ISOLATED SPINAL CORD OF THE TOAD[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1990(1).
Authors:Zhao Fangli Mei Jun
Institution:Department of Brain and Nerve
Abstract:This paper reports the effect of sodium selenite on dorsal root potentials(DR-DRP; VR-DRP)in the isolated toad spinal cord. The results indicate that selenite has a double phase effect or dorsal root potentials, that is, increasing the amplitude first, and then decreasing it. Using sucrose gap technique, we have proved that selenite has a dcoplarization effect on the dorsal roots. Further experiments indicate that spontaneous dorsal root potentials induced by selenite are attributed to its actions on the interneurons activities of the spinal cord. In addition, the mechanism of selenite's effects was discussed.
Keywords:Selenite  Dorsal root potentials  Sponta neous dorsal root potentials
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