| 不截肢治疗骨肉瘤 |
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| 引用本文： | 胡东岳,薛颖,许新军,胡堪锦,马志成,殷培朴.不截肢治疗骨肉瘤[J].西安交通大学学报(医学版),1984(3). |
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| 作者姓名： | 胡东岳 薛颖 许新军 胡堪锦 马志成 殷培朴 |
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| 作者单位： | 西安医学院第一附属医院，西安医学院第一附属医院，西安医学院第一附属医院，西安医学院第一附属医院，西安医学院第一附属医院，西安医学院第一附属医院 |
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| 摘 要： | 骨肉瘤的传统疗法是高位截肢,关节离断。预后很差,据统计五年生存率只有5—20％。自1972年Jaffe和Coites发表临床应用超大剂量氨甲碟呤以来,将五年生存率提高达36—77％该组收治二例股骨远端骨肉瘤,治疗方法是:盐酸氮芥动脉区域灌注,肿瘤切除灭活再植,超大剂量氨甲喋呤化疗,甲酰四氢叶酸钙抢救(HD—MTX—CF)不仅保住了肢体,而且患者上下樓不用付木,近期疗效满意。
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| 关 键 词： | 肉瘤骨原性 甲氨喋呤 关节切断术 |
Non-Amputation for the Treatment of Osteogenic Sarcoma |
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| Hu Dongyue et al.Non-Amputation for the Treatment of Osteogenic Sarcoma[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1984(3). |
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| Authors: | Hu Dongyue |
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| Abstract: | The conventional treatment of osteogenic sarcoma is a high amputation as well as disarticulation. The prognosis is poor and the 4-year survival rate is 5-20％. We treated two patients with distal femur osteogenic sarcoma. First we used mechlorelthamini hydrochlorici to infuse the local artery, and then removed the tumor tissue. After being inactivated with 95％ alcochal, the section was replanted into the original place. After operation, we used large doses of methotrexate with citrovorum factor (HD-MTX-CF), with satisfactory results. The leg was saved. Key words: Sarcoma; Osteogenic methotrexate; Non-amputation; Disarticulation |
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| Keywords: | Sarcoma Osteogenic methotrexate Non-amputation Disarticulation |
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