| 用聚乙二醇沉淀法检测类风湿性关节炎患者循环免疫复合物 |
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| 引用本文： | 郭珍,张培毅,王兰君,刘郁明.用聚乙二醇沉淀法检测类风湿性关节炎患者循环免疫复合物[J].西安交通大学学报(医学版),1983(4). |
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| 作者姓名： | 郭珍 张培毅 王兰君 刘郁明 |
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| 作者单位： | 西安医学院克山病研究室免疫组，西安医学院克山病研究室免疫组，西安医学院第二附属医院检验科，陕西省横山县医院 进修人员 |
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| 摘 要： | 本文推荐一种利用聚乙二醇沉淀、紫外分光光度计检测循环免疫复合物的改良方法,利用这一方法检测了53例正常人免疫复合物,其平均值为0.249±0.058;其80％正常值上限为0.298。并检测了63例类风湿关节炎患者的循环免疫复合物其平均值为0.314±0.102。二者有非常显著的差别(t=4.24;p<0.001)。如以超过0.298为阳性,则类风湿关节炎阳性数为25例,阳性率占40％(25/63)。这一方法操作简便、重复性强、有利于临床应用,便于在基层推广。
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Detection of Circulating Immune Complexes(CIC) by Simplified Assays with Polyethylene Glycol in Rheumatoid Arthritis(RA) |
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| Abstract: | In this Paper, a polyethylene glycol Precipitation method for the detection of circulating immune complexes in human serum is recommended. The serum samples obtained from 53 normal individuals were tested and showed a mean immune complex(IC)value of 0.240+0.058, and 80％ normal upper limit was 0.298. However, the mean IC value of Serum obtained from 63 patients with rheumatoid arthritis was 0.314+0.102. The difference between the control and RA groups was significant (t=4.24; P<0.001). The Positive rate of measuring CIC in RA patients was 40％(26/63). This method is simple and reliable. It provides a useful routine method in clinical practice. |
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