| 脑的神经再生 |
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| 引用本文： | 刘勇,刘建新.脑的神经再生[J].西安交通大学学报(医学版),2010,31(2). |
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| 作者姓名： | 刘勇 刘建新 |
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| 作者单位： | 西安交通大学医学院神经生物学研究所,陕西西安,710061 |
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| 摘 要： | 侧脑室室管膜下区和齿状回的颗粒下区的神经祖细胞通过增殖和分化产生新生细胞的神经再生过程终生存在于哺乳动物脑内.本文综述了神经祖细胞增殖、迁移、分化并功能性整合的调节机制,并对病理条件下的神经再生以及脑内神经再生研究目前存在的问题和局限性作了进一步的讨论和分析,希望对神经系统疾病的替代治疗研究具有一定的启示作用.
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| 关 键 词： | 神经再生 神经干细胞 神经祖细胞 室管膜下区 齿状回颗粒下层 |
Neurogenesis in the brain |
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| LIU Yong,LIU Jian-xin.Neurogenesis in the brain[J].Journal of Xi‘an Jiaotong University:Medical Sciences,2010,31(2). |
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| Authors: | LIU Yong LIU Jian-xin |
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| Institution: | LIU Yong,LIU Jian-xin(Institute of Neurobiology,Medical School of Xi\'an Jiaotong University,Xi\'an 710061,China) |
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| Abstract: | Neurogenesis is sustained throughout adulthood in the mammalian brain due to the proliferation and differentiation of adult neural progenitor cells found in the subventricular zone of the lateral ventricles and subgranular zone of the dentate gyrus.This review covers recent findings that elucidate different aspects of regulation of neurogenesis,including proliferation,migration and differentiation into mature neurons and functional integration into the existing neural circuits.Furthermore,this review also d... |
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| Keywords: | neurogenesis neural stem cell neural progenitor cell subventricular zone subgranular zone of the dentate gyrus |
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