| 纳米磷酸盐/聚磷酸钙纤维/聚乳酸骨与软骨组织工程支架复合材料研究 |
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| 引用本文： | 朱凌云,王彦平,张红梅.纳米磷酸盐/聚磷酸钙纤维/聚乳酸骨与软骨组织工程支架复合材料研究[J].兰州铁道学院学报,2011(3). |
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| 作者姓名： | 朱凌云 王彦平 张红梅 |
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| 作者单位： | 兰州交通大学机电工程学院; |
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| 基金项目： | 甘肃省自然科学基金项目(096RJZA085) |
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| 摘 要： | 采用溶媒浇铸、粒子滤取技术与气体发泡相结合的方法制备出纳米磷酸盐/CPP/PLLA骨与软骨组织工程支架复合材料;测试了该支架复合材料的物理、力学及降解性能,并用扫描电子显微镜对其微观结构进行了观察.实验结果表明:纳米磷酸盐/CPP/PLLA骨与软骨组织工程支架复合材料具有三维、连通、微孔网状结构,并具有较高的空隙率和较好的压缩模量,还具有良好的降解性能和生物相容性,是比较理想的骨和软骨组织工程支架材料.
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| 关 键 词： | 组织工程 支架 骨和软骨 复合材料 降解 |
Fabrication and Properties of Nanometer Phosphate/CPP/PLLA Composite of Scaffold for Bone and Cartilage Tissue Engineering |
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| ZHU Ling-yun,WANG Yan-ping,ZHANG Hong-mei.Fabrication and Properties of Nanometer Phosphate/CPP/PLLA Composite of Scaffold for Bone and Cartilage Tissue Engineering[J].Journal of Lanzhou Railway University,2011(3). |
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| Authors: | ZHU Ling-yun WANG Yan-ping ZHANG Hong-mei |
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| Institution: | ZHU Ling-yun,WANG Yan-ping,ZHANG Hong-mei(School of Mechatronic Engineering,Lanzhou Jiaotong University,Lanzhou,Lanzhou 730070,China) |
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| Abstract: | Nanometer phosphate /CPP/PLLA composite of the scaffold for tissue engineering was fabricated with a solvent-casting,particulate-leaching method.The properties of physical mechanics and degradation rates in vitro are tested.The experimental results show that the composites have high porosity,good biodegradability and compressive modulus as well as 3-D,connectivity network microstructures.Therefore,this composite can be one of scaffold materials for tissue engineering with potential broad applicability. |
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| Keywords: | tissue engineering scaffold bone and cartilage composite materials degradation |
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