| 绞股蓝总皂甙防治慢性肾功能衰竭的实验研究 |
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| 引用本文： | 孙万森,乔成林,刘锐,张晓东,程卫. 绞股蓝总皂甙防治慢性肾功能衰竭的实验研究[J]. 西安交通大学学报(医学版), 1998, 0(2) |
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| 作者姓名： | 孙万森 乔成林 刘锐 张晓东 程卫 |
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| 作者单位： | 西安第二临床医学院中医学教研室!西安，710004，西安第二临床医学院中医学教研室!西安，710004，西安二临床医学院中医学教研室!西安，710004，西安第二临床医学院中医学教研室!西安，710004，西安第二临床医学院中医学教研室!西安，710004 |
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| 摘 要： | 为了观察绞股蓝总皂甙（GP）对慢性肾功能衰竭（CRF）的作用。用腺嘌呤灌胃建立大鼠CRF模型，并用GP进行防治。结果表明GP组大鼠肾功能明显改善，贫血明显纠正，和病理组大鼠比较差异显著（P＜0．01或＜0．05）。肾脏病理检查显示，GP组肾小球结构基本正常，间质纤维化不明显，而病理组病损严重，间质明显纤维化。提示GP具有改善肾功能、纠正肾性贫血、延缓CRF进展的作用。
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| 关 键 词： | 绞股蓝总皂甙 肾功能衰竭 腺嘌呤 |
EXPERIMENTAL STUDY OF GYPENOSIDE ON PREVENTING CHRONIC RENAL FAILURE |
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| Sun Wansen,Qiao Chenglin,Liu Rui et al. EXPERIMENTAL STUDY OF GYPENOSIDE ON PREVENTING CHRONIC RENAL FAILURE[J]. Journal of Xi‘an Jiaotong University:Medical Sciences, 1998, 0(2) |
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| Authors: | Sun Wansen Qiao Chenglin Liu Rui et al |
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| Abstract: | Effect of Gypenoside (GP) on preventing chronic renal failure (CRF) was observed.Model of CRF in rats was established by gastrogavaging with adenine. Gypenoside (GP) was used to treat CRF. The results showed improvement of renal function or correction of anemia was more abvious in GP group than that in control group (P ＜0.01 or＜0. 05).Compared with GP group,there was distinct inter |
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| Keywords: | Gypenoside renal failure adenine stitial fibrosis and construction damage of glomerulus in control group. The results indicate that GP could improve renal function and correct anemia so it has function of retarding the progress of CRF |
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