| 容量超负荷型及容量合并压力超负荷型心脏心肌胶原的变化 |
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| 引用本文： | 封启明,刘治全,杨鼎颐.容量超负荷型及容量合并压力超负荷型心脏心肌胶原的变化[J].西安交通大学学报(医学版),1997(1). |
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| 作者姓名： | 封启明 刘治全 杨鼎颐 |
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| 作者单位： | 西安第一临床医学院心内科!西安710061 |
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| 摘 要： | 为研究容量超负荷型心脏病心肌胶原含量的改变，我们应用羟脯氨酸法，观察了19例先天性心脏病房／室间隔缺损患者右心耳心肌胶原含量的变化，并与5例健康意外死亡者作对照，结果表明：容量超负荷型心脏患者，无论是房间隔缺损还是空间隔缺损，心肌胶原含量与正常人相比显著降低，但当房／室间隔缺损合并肺动脉高压后，心肌胶原含量则增多，与正常人相比有显著性差异。
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| 关 键 词： | 容量超负荷型 压力超负荷型 心肌胶原含量 |
THE CHANGES OF COLLAGEN CONCENTRATION IN VOLUME-OVERLOADED AND VOLUME-PRESSURE-OVERLOADED HUMAN HEART |
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| Feng Qiming,Liu Zhiquan,Yang Dingyi.THE CHANGES OF COLLAGEN CONCENTRATION IN VOLUME-OVERLOADED AND VOLUME-PRESSURE-OVERLOADED HUMAN HEART[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1997(1). |
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| Authors: | Feng Qiming Liu Zhiquan Yang Dingyi |
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| Abstract: | To investigate the changes of collagen concentration in volume-overloaded heart, westudied 19 patients with ventricular septum dificiency (VSD) and/or atrium septum dificiency (ASD).19-patients were divided into 3 groups: VSD, ASDand VSD and/or ASD with pulmonary hypertension. 5 healthy control persons died by accident.The collagen concentrations were measured usinghydroxyproline method. The collagen concentrations in volume-overloaded hearts, both in VSD andASD hearts were decreased significantly comparedwith control group, whereas with pulmonary hypertension, the collagen concentrations in VAD and/orASD hearts were significantly increased and obviously different from those in the normal healthy persons. |
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| Keywords: | volume-overloaded pressure-overloaded: collagen concentration |
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