| 硒对大鼠骨骼肌线粒体单胺氧化酶活性的影响 |
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| 引用本文： | 周兰华,范高峰,徐光禄,王世臣,薛文岚.硒对大鼠骨骼肌线粒体单胺氧化酶活性的影响[J].西安交通大学学报(医学版),1992(1). |
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| 作者姓名： | 周兰华 范高峰 徐光禄 王世臣 薛文岚 |
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| 作者单位： | 西安医科大学生物化学教研室
(周兰华，范高峰)，西安医科大学克山病研究室
(徐光禄，王世臣)，西安医科大学克山病研究室(薛文岚) |
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| 摘 要： | 本文动态观察了克山病病区低硒粮喂养大鼠骨骼肌线粒体单胺氧化酶(MAO)活性的变化。于饲养后第30d、第60d及第90d分批处死大鼠,取肌肉分离线粒体,用荧光法测定MAO活性。其结果在实验的初期和中期(第30d和第60d)低硒组大鼠与补硒组或常备饲料组之间MAO活性均无显著差异,到第90d才出现显著差异。可能骨骼肌线粒体对低硒的损害敏感性低,耐受力强。
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| 关 键 词： | 硒 骨骼肌线粒体 大鼠 单胺氧化酶 |
EFFECTS OF Se ON MONOAMINE OXIDASE ACTIVITY |
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| Zhou Lanhua,Fan Gaofeng,Xu Guanglu,et al.EFFECTS OF Se ON MONOAMINE OXIDASE ACTIVITY[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1992(1). |
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| Authors: | Zhou Lanhua Fan Gaofeng Xu Guanglu |
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| Institution: | Xi'an Medical University |
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| Abstract: | The changes of skeletal muscle mitochondral monoamine oxidase (MAO) activity in rats fed with low Se grains from a Keshan-disease area were observed. The rats were killed at the time for feeding 30, 60 and 90 days respectiely. The mitochondrium of skeletal muscle was isolated MAO activity was determined with fluorescent methed. The results showed that in low-Se group the mitochondrial MAO activity was significantly decreased only at the time for 90 days feeding however GSH-px activity in red blood cells and Se content in plasma were significantly decreased at all experimental period as compared to Se-supplemented or stock died group. |
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| Keywords: | selenium monoamine oxidase rat mitochondrium |
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