| 酸枣仁总皂苷对大鼠急性心肌缺血的保护作用 |
| |
| 引用本文： | 张玮,袁秉祥,于晓江,孙红,夏传涛.酸枣仁总皂苷对大鼠急性心肌缺血的保护作用[J].西安交通大学学报(医学版),2005,26(4):333-335. |
| |
| 作者姓名： | 张玮 袁秉祥 于晓江 孙红 夏传涛 |
| |
| 作者单位： | 1. 西安交通大学,理学院,陕西西安,710061
2. 西安交通大学,医学院,陕西西安,710061 |
| |
| 摘 要： | 目的研究酸枣仁总皂苷对大鼠急性心肌缺血的保护作用,以及对心肌梗死面积的影响。方法用结扎冠状动脉左前降支(LAD)致大鼠急性心肌缺血,以心肌梗死面积和心电图(ECG)变化评价酸枣仁总皂苷的药物作用。结果与模型对照组比较,酸枣仁总皂苷给药组可显著缩小心肌梗死面积;ECG显示各给药组与病理模型组比较心率、S-T段、T波值均有明显降低。结论预防性给予酸枣仁总皂苷可显著缩小LAD结扎所致大鼠心肌梗死面积,具有保护心肌的作用。
|
| 关 键 词： | 酸枣仁 酸枣仁总皂甙 心肌梗死 急性心肌缺血 |
| 文章编号： | 1671-8259(2005)04-0333-03 |
| 收稿时间： | 2004-09-14 |
| 修稿时间： | 2005-01-10 |
Protective action of Semen Ziziphi Spinosaeand on acute myocardial ischemia |
| |
| Zhang Wei,Yuan Bingxiang,Yu Xiaojiang,Sun Hong,Xia Chuantao.Protective action of Semen Ziziphi Spinosaeand on acute myocardial ischemia[J].Journal of Xi‘an Jiaotong University:Medical Sciences,2005,26(4):333-335. |
| |
| Authors: | Zhang Wei Yuan Bingxiang Yu Xiaojiang Sun Hong Xia Chuantao |
| |
| Abstract: | Objective To study the protective action of Semen Ziziphi Spiosaeand on acute myocardial ischemia and its effecte on infarcted area. Methods Left anterior descending(LAD) of coronary artery was ligated to cause the big rat's acute myocardial ischemia, and electrocardiogram (ECG) was used to appraise the effect of sour jujube kernel total soap on the myocardial infarcted area. Results Compared with control group, the experimental group treated with sour jujube kernel total soap glucosidal showed significantly smaller infarcted area; and ECG showed the heart rhythm, S-T piece and T wave value were significantly decreased in the experimental group. Conclusion Sour jujube kernel total soap glucosidal can reduce the myocardial infarcted area caused by ligature of LAD, so as to protect the cardiac muscle. |
| |
| Keywords: | Ziziphas Jujuba Mill Semen Ziziphi Spinosa myocardial infarction acute myocardial ischemia |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
