| 喷漆工的姊妹染色单体交换频率分析 |
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| 引用本文： | 周叔竽,胡晓蓉,林田,师娟子,姬志峰,谢海波.喷漆工的姊妹染色单体交换频率分析[J].西安交通大学学报(医学版),1989(2). |
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| 作者姓名： | 周叔竽 胡晓蓉 林田 师娟子 姬志峰 谢海波 |
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| 作者单位： | 西安医科大学医学遗传学教研室
(周叔竽，胡晓蓉，林田，师娟子，姬志峰)，西安医科大学医学遗传学教研室(谢海波) |
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| 摘 要： | 本文分析了30名喷漆工及两个对照组的30名姊妹染色体交换(SCE)的频率.实验结果显示在这三组之间的SCE 频率有显著的差异。这些喷漆工的SCE/细胞频率(6.14±1.71;P<0.001)显著地高于这两个对照组(4.88±1.29;2.49±0.42;P<0.001),而这三组的SCE/染色体频率之间的差异并不显著(P>0.20)。这表明喷漆的物质会使工人产生一定的细胞遗传学效应。BrdU 标记染色体的方法对某些有毒性物质是一种敏感的指示剂。
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| 关 键 词： | 喷漆工 姊妹染色单体交换 5-溴脱氧尿嘧啶核苷 敏感指示剂 |
ANALYSIS ON THE FREQUENCY OF SISTER CHROMATID EXCHANGES(SCE)IN SPRAY PAINTERS |
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| Zhou Shuyu,et al.ANALYSIS ON THE FREQUENCY OF SISTER CHROMATID EXCHANGES(SCE)IN SPRAY PAINTERS[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1989(2). |
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| Authors: | Zhou Shuyu |
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| Institution: | Department of Medical Genetics |
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| Abstract: | The SCE frequency of 30 spray painters and 30 per-sons from two control groups was analysed.The results re-vcaled that there were significant differences in SCE fre-quency among the three groups.The SCE/cell frequenciesof these spray painters(6.14±1.71;p<0.001)weresignificantly higher than the both control groups(4.88±1.29;2 49±0.42;p<0.001)and theSCE/chromosome frequencies of the three groups werenot significant(p>0.20).It was shown that the sub-stances of spraying the aeroplanes with paint might havecertain cytogenetic effects on workers and proved that themethod of BrdU marker chromosome wasa sensitive indi-cator to some toxic substances. |
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| Keywords: | spray painter SCE BrdU sensitive indicator |
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