MR ASSESSMENT OF LUNG DEVELOPMENT IN FETAL ANOMALIES USING RATIO OF LUNG TO LIVER SIGNAL INTENSITIES |
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| Authors: | LIU Ming ZHANG Yu-zhen FENG Yun LI Yu-hua |
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| Institution: | LIU Ming(Deparment of Radiology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200092, China)；ZHANG Yu-zhen(Deparment of Radiology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200092, China)；FENG Yun(Deparment of Radiology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200092, China)；LI Yu-hua(Deparment of Radiology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200092, China)； |
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| Abstract: | Objective To evaluate the monitoring and diagnostic potential of MR in fetal lung development using lung signal intensity changes in the fetus. Methods The lung-to-liver intensity ratio was calculated by means of region-of-interest analysis in all 35 fetuses including 7 bilateral urinary anomalies, 9 unilateral urinary anomalies, 5 pulmonary anomalies, and 14 others. Results All fetuses with urinary anomalies and pulmonary anomalies showed low ratio of lung-to-liver signal intensity. Conclusion Low ratio of lung-to-liver signal intensity on MR imaging indicates pulmonary hypoplasia after 22 weeks' gestation. |
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