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大鼠血浆雌二醇、睾酮水平的测定及意义
引用本文:张万年,邹丽容,卢兴,杨继声.大鼠血浆雌二醇、睾酮水平的测定及意义[J].西安交通大学学报(医学版),1986(1).
作者姓名:张万年  邹丽容  卢兴  杨继声
作者单位:西安医科大学病理生理学教研室 (张万年,邹丽容,卢兴),西安医科大学病理生理学教研室(杨继声)
摘    要:本文应用放射免疫方法测定了正常雌、雄大鼠血浆雌二醇、睾酮的水平及其雌二醇/睾酮比值。发现雄鼠血浆睾酮为270.0±46.2ng/100ml,雌二醇为62.1±2.8Pg/ml,雌二醇/睾酮比值为0.040±0.008;雌鼠血浆雌二醇、睾酮及其雌二醇/睾酮比值虽与动情周期有关,但总均值雌二醇为55.4±3.7pg/ml,睾酮为51.8±3.1ng/100ml,雌二醇/睾酮比值为0.121±0.014。我们认为这些数值,可以作为基础状态下正常大鼠血浆雌二醇、睾酮及其雌二醇/睾酮比值的参数,供实验研究参考。


DETERMINATION AND SIGNIFICANCE OF PLASMA ESTRADIOL AND TESTOSTERONE LEVELS IN RATS
Zhang Wannian,et al.DETERMINATION AND SIGNIFICANCE OF PLASMA ESTRADIOL AND TESTOSTERONE LEVELS IN RATS[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1986(1).
Authors:Zhang Wannian  
Institution:Department of Pathophysiology
Abstract:The estradiol (E_2) and testrosterone (T) levels in the Plasma of normal male and female rats and their E_2/T ratio were measured by radioimmunoassay. We have found that in the male rats the plasma testosterone level was 270.0±46.2 ng/100ml,the estradiol level was 62.I ±2.8 pg/ml and the E_2/T ratio wa(?) 0.040±0.008; in the female rats, although the estradiol and testosterone levels of the plasma and the E_2/T ratio changed with their estrous cycle, but the mean values of estradiol,testosterone and the E_2/T ratio were 55.4±3.7 pg/ml,51.8±3.1 ng/100 ml and 0.124±0.014 respectively. We suppose that these values may serve as normal values in the basic state and may be used for reference in experimental studies.
Keywords:rats  estradiol  testosterone  estrous cycle
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