| NPY神经纤维在大鼠心脏的分布及增龄变化 |
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| 引用本文： | 赵根然,杨月鲜,孔祥云,凌凤东,徐鹏霄. NPY神经纤维在大鼠心脏的分布及增龄变化[J]. 西安交通大学学报(医学版), 1995, 0(3) |
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| 作者姓名： | 赵根然 杨月鲜 孔祥云 凌凤东 徐鹏霄 |
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| 作者单位： | 西安医科大学人体解剖学教研室，西安医科大学人体解剖学教研室，西安医科大学人体解剖学教研室，西安医科大学人体解剖学教研室，中国武警医学院 西安710061，西安710061，西安710061，西安710061 |
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| 基金项目： | 国家自然科学基金资助项目 |
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| 摘 要： | 用免疫细胞化学ABC法在光镜和电镜下观察了不同月龄组SD大鼠心脏神经肽酪氨酸(NPY)神经纤维的分布特征及其衰老变化。结果发现:心脏各部位、各结构具有不同密度、不同形式的NPY神经分布,纤维均为膨体型。电镜下,神经纤维行于心肌间隙并与心肌细胞贴近,轴浆内充满NPY阳性反应颗粒。随月龄增加,神经纤维密度下降,纤维形态及分布形式发生改变,对心脏支配减弱。此外,在心内还发现NPY神经节。
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| 关 键 词： | 心脏 神经肽酪氨酸 增龄变化 免疫细胞化学 |
DISTRIBUTION AND AGING CHANGES OF NEUROPEPTIDE Y(NPY)-LIKE IMMUNOREACTIVE NERVE FIBERS IN RAT HEARTS |
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| Xu Pengxiao Zhao Genran,Yang Yuexian,et al. DISTRIBUTION AND AGING CHANGES OF NEUROPEPTIDE Y(NPY)-LIKE IMMUNOREACTIVE NERVE FIBERS IN RAT HEARTS[J]. Journal of Xi‘an Jiaotong University:Medical Sciences, 1995, 0(3) |
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| Authors: | Xu Pengxiao Zhao Genran Yang Yuexian et al |
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| Affiliation: | Department of Anatomy |
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| Abstract: | In this study, different aged SD rats were used by immunocytochemical method (ABC technique) and electron microscope to investigate the distributional pattern and aging changes of the NPY nerve fibers in rat hearts. The main results are as follows; (1) The various densities of the NPY nerve fibers were seen in all parts of the hearts. (2) The distributional pattern of the fibers were different in each part (such as stria. vantricles, coronaryvessels and valves). (3)A few groups of NPY-like cell bodies were found in the hearts.(4) Under electron microscope, the NPY nerve fibers were seen in close contact with cardiac mucsle cells, there were a lot of the NPY immunoreactive particales in the axo-plasms.(5) With aging, the densities of the NPY fibers tended to attenuation in all parts of the hearts. |
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| Keywords: | heart aging changes neuropeptide Y imraunocytochemistry |
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