| THE ACTION OF CAPTOPRIL ON SCAVENGING OXYGEN FREE RADICALS |
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| 作者姓名： | 李淳成 侯立业 |
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| 作者单位： | Department Of Cardiothoracic Surgery，Second Affiliated Hospital，Xi'an MedicalUniversity，Xi'an 710004 |
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| 摘 要： | ＴＨＥＡＣＴＩＯＮＯＦＣＡＰＴＯＰＲＩＬＯＮＳＣＡＶＥＮＧＩＮＧＯＸＹＧＥＮＦＲＥＥＲＡＤＩＣＡＬＳ（李淳成）（侯立业）ＬｉＣｈｕｎｃｈｅｎｇ；ＨｏｕＬｉｙｅ；（ＤｅｐａｒｔｍｅｎｔＯｆＣａｒｄｉｏｔｈｏｒａｃｉｃＳｕｒｇｅｒｙ，ＳｅｃｏｎｄＡｆｆｉ...
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THE ACTION OF CAPTOPRIL ON SCAVENGING OXYGEN FREE RADICALS |
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| Li Chuncheng,Hou Liye,.THE ACTION OF CAPTOPRIL ON SCAVENGING OXYGEN FREE RADICALS[J].Academic Journal of Xi’an Jiaotong University,1996(1). |
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| Authors: | Li Chuncheng Hou Liye |
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| Abstract: | The protective effect of captopril on ischemic myocardium was studied in 40 patients with congenital heart disease accompanied with pulmonary hypertention.Twenty of these patients received captopril 50 mg b.i.d.for three months preoperatively (Group A).The other 20 patients without pretreatment with captopril were used as controls (Group B).In Group A,the cardiac output increased and the pulmonary pressure decreased significantly in the first 24 hours postoperatively,indicating a high cardiac output with a low vascular resistance.The differences or CPK,CPKMB,LDH release between Group A and Group B were highly significant or siguificant from the end of operation to 24 hours postoperatively. Myocardial protection in the reduction of the release of CPK, CPK-MB, LDH might be attributed to action on scavenging oxygen free radicals. |
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| Keywords: | aptoprill myocardial protection oxygen free radicals |
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