| 克山病病区儿童红细胞免疫功能及其机理研究 |
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| 引用本文： | 葛克亮,郭珍,张培毅,薛文岚,杨占田,梁文升.克山病病区儿童红细胞免疫功能及其机理研究[J].西安交通大学学报(医学版),1992(1). |
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| 作者姓名： | 葛克亮 郭珍 张培毅 薛文岚 杨占田 梁文升 |
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| 作者单位： | 西安医科大学克山病研究室，西安医科大学克山病研究室，西安医科大学克山病研究室，西安医科大学克山病研究室，西安医科大学克山病研究室，西安医科大学克山病研究室 西安 710061，西安 710061，西安 710061，西安 710061，西安 710061，西安 710061 |
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| 基金项目： | 陕西省卫生厅专题科研资助项目 |
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| 摘 要： | 本文报道了克山病病区健康儿童硒含量和红细胞免疫功能及血清调节因子的检测结果。发现病区健康儿童硒含量及红细胞C_(3b)花环率明显低于非病区健康儿童(P<0.01),而病区健康儿童红细胞免疫粘附抑制率却明显高于非病区健康儿童(P<0.01)。但免疫复合物花环率和免疫粘附促进率两组儿童无显著差异(P>0.05)。提示病区健康儿童红细胞免疫功能低下,可能与缺硒和血清的免疫粘附抑制因子增加有关。
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| 关 键 词： | 克山病 红细胞免疫 硒 |
THE STUDY OF RED CELL IMMUNITY STATE OF THE CHILDREN IN KESHAN DISEASE AREA |
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| Ge Keliang,Guo Zhen,Zhang Peiyi,et al.THE STUDY OF RED CELL IMMUNITY STATE OF THE CHILDREN IN KESHAN DISEASE AREA[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1992(1). |
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| Authors: | Ge Keliang Guo Zhen Zhang Peiyi |
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| Institution: | Research Laboratory of Keshan Disease |
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| Abstract: | Red cell immunologic adherent function and Se quantity were measured in 48 normal children of Keshan disease area and the reaction of red cell C3bR to these children. The results showed that the Se quantity and the rosette formation rate of red cell C3bR of normal children in Keshan disease area were significantly lower than that in the control(P<0.01), while the rosette forming inhibitory rate of red cell C3bR was significantly higher than that in the control (P<0.01), but the rosette formation rate of red cell immune complex and the rosette forming promotive rate of red cell C3bR were no difference as compared with that in the control (P>0.05). |
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| Keywords: | Keshan disease red-cell immunity selenium (Se) |
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