| The experimental observation on the repairing spinal cord injury by olfactory ensheathing cells allograft of different sources |
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| 引用本文： | 张纯 贺西京 常瑞 兰宾尚 李浩鹏. The experimental observation on the repairing spinal cord injury by olfactory ensheathing cells allograft of different sources[J]. 西安交通大学学报(英文版), 2007, 19(2): 212-216 |
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| 作者姓名： | 张纯 贺西京 常瑞 兰宾尚 李浩鹏 |
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| 作者单位： | Department of Orthopaedics, the Second Affiliated Hospital, Medical School of Xi＇an J iaotongUniversity, Xi＇an 710004, China |
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| 摘 要： | Objecttive To observe the repaired effect of distinct source olfactory ensheathing cells （OECs） on spinal cord injury （SCI） rats. Methods These OECs were dissociated from olfactory bulb and olfactory mucosa of SD rats and transplanted to the injuried region of spinal cord injury rats. The function of nerve, motor evoked potential of hind legs and the histopathlogical diversities of injuried spinal cord were observed. Results The OECs grafts into the SCI area could survive longer time. The BBB scale, incubation stage of EP and histopathologic manifestations showed that the group with transplanted OECs regained more improvement in hindlimb than the control group. Conclusion The OECs of two sources have the same ability to regain and improve the axonal function which can promote axons regeneration of SCI.
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| 关 键 词： | 嗅觉细胞 细胞培养 细胞移植 脊髓损伤 |
| 文章编号： | 1671-8267（2007）02-0212-05 |
The experimental observation on the repairing spinal cord injury by olfactory ensheathing cells allograft of different sources |
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| Zhang Chun,He Xijing,Chang Rui,Lan Binshang,Li Haopeng. The experimental observation on the repairing spinal cord injury by olfactory ensheathing cells allograft of different sources[J]. Academic Journal of Xi’an Jiaotong University, 2007, 19(2): 212-216 |
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| Authors: | Zhang Chun He Xijing Chang Rui Lan Binshang Li Haopeng |
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| Abstract: | Objecttive To observe the repaired effect of distinct source olfactory ensheathing cells (OECs) on spinal cord injury (SCI) rats. Methods These OECs were dissociated from olfactory bulb and olfactory mucosa of SD rats and transplanted to the injuried region of spinal cord injury rats. The function of nerve, motor evoked potential of hind legs and the histopathlogical diversities of injuried spinal cord were observed. Results The OECs grafts into the SCI area could survive longer time. The BBB scale, incubation stage of EP and histopathologic manifestations showed that the group with transplanted OECs regained more improvement in hindlimb than the control group. Conclusion The OECs of two sources have the same ability to regain and improve the axonal function which can promote axons regeneration of SCI. |
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| Keywords: | olfactory ensheathing cells (OECs) cell culture spinal cord injury (SCI) cell transplantation |
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