| 大骨节病病区与非病区儿童血浆环核苷酸磷酸二脂酶的测定 |
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| 引用本文： | 任瑛云.大骨节病病区与非病区儿童血浆环核苷酸磷酸二脂酶的测定[J].西安交通大学学报(医学版),1984(1). |
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| 作者姓名： | 任瑛云 |
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| 作者单位： | 西安医学院克山病研究室 |
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| 摘 要： | <正> 环型腺苷酸(cAMP),几乎存在于机体内的每个细胞,它是由激素(机体的第一化学信使)将生物化学信息传递给细胞膜上的受体,使膜上的腺苷酸环化酶(AC)活化,从而催化细胞内的三磷酸腺苷(ATP)转变成cAMP。cAMP则直接控制或调节细胞内的新陈代谢、离子通透性以及许多生理功能,它被称为机体的“第二化学信使”。而环式腺苷酸磷酸二脂酶(cAMP-PDE),则是催化cAMP分解的酶,凡有cAMP存
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The Activities of the cAMP-PDE in Children's Plasma in Kasehin-Beck Disease Areas |
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| Abstract: | The activities of cAMP-PDE and cGMP-PDE in children's plasma were determined in Kaschin-Beck's Disease areas and non-affected areas in Shaanxi Province in April 1983. The unit of cAMP-PDE and cGMP-PDE activities in affected areas was 10.46±0.78 and 7.12±0.33, but in non-affected areas 26.66±3.72 and 16.40±1.38 respectively. Obviously, the activities of both enzymes are quite different in affected and non-affected araes, The enzyme activities in affected areas are signiticantly lower than in non-affected areas (P<0.01). |
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