不同血型不同时期库存血红细胞免疫功能的初步观察

通过对 6 0份血样行库存模拟试验 ,于第 1、3、7、14、2 1日分别测定红细胞免疫功能。结果显示 :库存当日红细胞 C3 b受体 (RBC- C3 b R)活性最高 ,从第 3日起随存放时间延长而逐渐降低 ,红细胞免疫复合物花环 (RBC- ICR)无明显变化。 B型血 RBC- C3 b RR在库存第 7日后降低 ,而其它血型 3日后降低 ,RBC- ICR除 O型在第 14日有一过性降低外 ,其它血型无变化。提示在输血治疗中 ,应考虑库存血红细胞免疫功能的降低对机体的影响。

Changes of erythrocyte immune function in stored blood on the differe nt types and times

Blood samples from 60 cases were stored in fridge for simulated test.Immune function of red blood cell was tested at the first、third、7th、14th、21th days separately.The results showed that the activity of RBC C 3bRR was highest at the first day and that the activity of RBC C 3bRR became lower and lower after the third day, but the amount of RBC ICR didnt change;The activity of type B blood RBC C 3bRR started to decend gradually at the 7th day ,but the activity of RBC C 3bRR in the other blood types started to descend at the third day;The amount of type o blood RBC ICR reduce on one occasion at the 14th day, and didnt change in the other blood types.Therefore, in course of treatment of blood transfusion, we should consider the changes of stored RBC immune function.