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| 大肠癌手术前后血清CEA与SIL-2R联合检测的临床意义 | |
| 引用本文： | 贾宗良,付向阳,王小芹. 大肠癌手术前后血清CEA与SIL-2R联合检测的临床意义[J]. 西安交通大学学报(医学版), 2000, 21(1) |
| 作者姓名： | 贾宗良 付向阳 王小芹 |
| 作者单位： | 1. 西安医科大学第一附属医院外科,西安,710061 2. 陕西省宝鸡市金台医院外科,721001 3. 西安医科大学一附院检验科 |
| 摘 要： | 对 4 2例大肠癌患者手术前后血清中癌胚抗原 (Carinoembryonle Antigen ,CEA)及可溶性白介素 - 2受体 (Solubleinter leukin- 2 receptor,SIL - 2 R)的检测结果显示 ,术前血清 CEA及 SIL - 2 R均高于对照组 (P <0 .0 1) ,且随 Duke′s分期增高而升高。术后血清 CEA较 SIL- 2 R下降快。但 SIL- 2 R在术后 10 d内反升高 ,尤其是 6例 Duke′s D期患者更明显 ,可能与肿瘤本身转移及手术对机体免疫功能抑制有关。CEA及 SIL- 2 R与肿瘤的病理类型无关。提示 ,术后定期联合监测 CEA及 SIL- 2 R可为临床观察肿瘤患者的病情变化、严重程度、监测疗效及判断预后提供依据 ,及早发现术后复发病人。 |
| 关 键 词： | 大肠 CEA SIL-2R |
The clinical significance of combinative measuring CEA and SIL-2R from patients with colorectal neoplasm during perioperational period |
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| Jia Zongliang,Fu Xiangyang,Wang Xiaoqin. The clinical significance of combinative measuring CEA and SIL-2R from patients with colorectal neoplasm during perioperational period[J]. Journal of Xi‘an Jiaotong University:Medical Sciences, 2000, 21(1) | |
| Authors: | Jia Zongliang Fu Xiangyang Wang Xiaoqin |
| Abstract: | Through measuring the level of CEA and SIL 2R from 42 patients with colorectal neoplasm, the results showed that the level of CEA and SIL 2R in preoperational patients were obviously higher than that in mormal mucosa (P<0.01) and in creased with Duke′s stage developing.The drop of CEA was faster than SIL 2R after operation.On the contrary, the level of Sil 2R increased in the first 10 days after operation, especially in 6 patients with Duke's D stage.These results indicated that combinative measuring the level of CEA and SIL 2R scheduledly can easily observe the clinical significances of the patients with colorctal neoplasm. |
| Keywords: | CEA SIL 2R colorectal neoplasm |
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