葡甲胺-cAMP(心先安)静脉注射对充血性心衰患者急性血液动力学效应 |
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引用本文: | 袁祖贻,祝家庆,刘艳,王燕妮,李明,刘维维. 葡甲胺-cAMP(心先安)静脉注射对充血性心衰患者急性血液动力学效应[J]. 西安交通大学学报(医学版), 2000, 21(6): 538-539 |
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作者姓名: | 袁祖贻 祝家庆 刘艳 王燕妮 李明 刘维维 |
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作者单位: | 西安交通大学第一医院心内科,西安 710061 |
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摘 要: | 目的 观察葡甲胺 cAMP对慢性心力衰竭 (CHF)患者的急性血液动力学效应。方法 1 0例中、重度CHF患者 ,静脉注射葡甲胺 cAMP(60mg 3~ 5min内缓慢注射 ) ,观察用药前后血流动力学参数变化。结果 用药后 1 0min ,患者心率减慢 ,平均肺动脉压 (mPAP)及肺嵌压(PCWP)下降 ,肺循环阻力 (PVR)和体循环阻力 (SVR)降低 ,心脏指数升高 ,持续作用 30min以上。结论 葡甲胺 cAMP对CHF患者具有良好的急性血液动力学效应 ,可改善心脏作功能力
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关 键 词: | 充血性心力衰竭 血液动力学 葡甲胺-cAMP |
文章编号: | 0258-0659(2000)06-538-02 |
修稿时间: | 2000-02-18 |
The acute hemodynamic effects of BTB-cAMP injection in patients with congestive heart failure |
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Abstract: | Objective To study the acute hemodynamic effects of benzylthiobutyl adenosine cyclic monophosphate(BTB-cAMP) injection in patients with congestive heart failure(CHF). MethodsTen patients with moderate to severe CHF were enrolled and operated by Swan-Ganz catheter to observe the acute hemodynamic effecs of BTB-cAMP injection. Results The mean value of pulmonaryarterial pressure(MPAP), pulmonary wedge pressure(PWP), pulmonary vessel resistance(PVR) and systemic vessel resistance (SVR) decreased significantly; The cardic index (CI) increased significantly. The heart beating rate slowed. Conclusions BTB-cAMP injection is beneficial acute hemodynamic effects in patients with CHF. |
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Keywords: | hemodynamics BTB-cAMP congestive heart failure |
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