| 衰竭心肌细胞膜及线粒体膜镧通透性改变的初步电镜观察 |
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| 引用本文： | 马爱群,刘治全,杨鼎颐,陈念祖,邵英杰.衰竭心肌细胞膜及线粒体膜镧通透性改变的初步电镜观察[J].西安交通大学学报(医学版),1995(3). |
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| 作者姓名： | 马爱群 刘治全 杨鼎颐 陈念祖 邵英杰 |
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| 作者单位： | 西安医科大学第一附属医院心内科，西安医科大学第一附属医院心内科，西安医科大学第一附属医院心内科，西安医科大学克山病研究室，西安医科大学克山病研究室 西安710061，西安710061，西安710061 |
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| 基金项目： | 国家自然科学基金资助项目,No.39200049 |
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| 摘 要： | 5例心功能处于不同状态心脏病人涪检心肌标本硝酸镧示踪电镜观察结果显示:5例均有镧颗粒进入心肌细胞内,分布于肌原纤维及线粒体,并部分进入线粒体内,使线粒体显像。进入细胞内、线粒体内镧颗粒的多少与心功能状态一致。反映了衰竭心肌细胞膜及线粒体膜通透性增加。提示生物膜通透性损伤参与心肌细胞衰竭发生发展过程。
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| 关 键 词： | 心力衰竭 细胞膜 线粒体 镧通透性 |
OBSERVATION OF PERMEABILITY OF LANTHANUM IN MYOCARDIAL CELL MEMBRANE AND MITOGHONDRIA MEMBRANE WITH HEART FAILURE |
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| Ma Aiqun. Liu Zhiquan,Yang dingyi,et al.OBSERVATION OF PERMEABILITY OF LANTHANUM IN MYOCARDIAL CELL MEMBRANE AND MITOGHONDRIA MEMBRANE WITH HEART FAILURE[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1995(3). |
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| Authors: | Ma Aiqun Liu Zhiquan Yang dingyi |
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| Abstract: | Endomyocardial biopsy samples of 5 patients who have different heart function states were observed by Lanthhanum Nitrate tracing electromicroscope. The result showed that Lan- thanum granules entered the myocardial cell of allthese 5 patients. The Lantanum granules scattered between the myofibril and mitochondria. Some granules entered the mitochondria, causing the imaging of the mitochondria. The more granules entered the mitocondria. the worse heart function the patient had. This shows that permeability of themyocardial cell membrane and mitochondria membrane in the patients with heart failure increase, which suggests the injury of the permeability of the biomembrane plays a roe in the developing process of the myocardial failure. |
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| Keywords: | heart failure cell membrane mitochondria permeability of Lanthanum |
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