正常成人神经传导远端复合肌肉动作电位参数值正常范围的建立

目的确定正常成人神经传导远端复合肌肉动作电位(CMAP)末端潜伏时和波幅的正常值范围,为诊断周围神经病提供依据。方法对245例正常健康志愿者的正中神经、尺神经、胫神经及腓总神经进行常规神经传导速度测定,分析其末端潜伏时和波幅,其结果按照不同年龄段、性别、体重、左右侧肢体分别进行统计学分析。结果性别、体重、左右侧肢体对远端CMAP参数值的影响无明显统计学差异。年龄是最主要的影响因素,40岁前后变化最大,主要影响的是各神经远端CMAP的波幅和正中神经末端潜伏时,表现为随着年龄的增大,波幅逐渐减低,末端潜伏时逐渐延长。结论正常成人远端CMAP各参数的正常值范围按40岁前后两个年龄段确定比较合理和实用。

Establishment of the normative ranges for nerve conduction values of distal compound muscle action potential

Objective To establish the normative ranges for nerve conduction values of distal compound muscle action potential(CMAP) latency and amplitude and to provide evidence for diagnosing peripheral neuropathy.Methods A total of 245 normal volunteers were recruited,and nerve conduction study was carried out on median nerve,ulnar nerve,tibial nerve and peroneal nerve.The distal latency and amplitude were analyzed.The data collected were tabulated and analyzed based on age,sex and weight in the EXCEL and SPSS systems.Results Gender,weight and sidedness had no effects on CMAP distal latency and amplitude.However,age had a significant effect on CMAP amplitude and median nerve distal latency.This age effect was more obvious for people around 40 years old.Distal latency was prolonged and amplitude was decreased with age increasing.Conclusion It is reasonable and clinically practicable to establish the normative ranges of distal CMAP according to two age groups: above and below 40 years old.