| 四乙脂慢性肝损伤模型的生化分析 |
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| 引用本文： | 袁素芬,邱培伦,刘俊田,王美纳,舒昌杰.四乙脂慢性肝损伤模型的生化分析[J].西安交通大学学报(医学版),1988(4). |
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| 作者姓名： | 袁素芬 邱培伦 刘俊田 王美纳 舒昌杰 |
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| 作者单位： | 西安医学院生物化学教研室
(袁素芬)，西安医学院药理学教研室
(邱培伦，刘俊田，王美纳)，西安医学院第一附属医院传染病学教研室(舒昌杰) |
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| 摘 要： | 用四氯化碳、乙醇和高脂肪饲料制成四乙脂慢性肝损伤动物模型,进行生化测定。实验结果:血清GPT、LDH_5和r球蛋白升高,清蛋白降低,肝中胶原明显增加。表明四乙脂慢性肝损伤动物模型的各项生化指标与慢性活动性肝炎患者相似。
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| 关 键 词： | 转氨酶 乳酸脱氢酶同工酶 胶原 清蛋白 r球蛋白 慢性活动性肝炎 |
BIOCHEMICAL ANALYSIS OF CHRONIC HEPATIC INJURY MODEL INDUCED BY TEF |
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| Yuan Sufen,et al.BIOCHEMICAL ANALYSIS OF CHRONIC HEPATIC INJURY MODEL INDUCED BY TEF[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1988(4). |
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| Authors: | Yuan Sufen |
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| Institution: | Department of Biochemistry |
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| Abstract: | Chronic hepatic injury animal model induced by TEF was made with carbontetrachloride, ethyl alcohol and a high-fat feed. An increase in serum GPT, LDH_5 and r-globulin, a decrease in serum albumin and a remarkable increase in hepatic collagen were found. The results indicated that all biochemical data obtained in this model is similar to those in patients with chronic active hepatitis. |
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| Keywords: | albumin、collagen、chronic active hepatitis、GPT、r-globulin、LDH_5 |
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