BLOOD FLOW PATTERN AND QUANTITATIVE STUDY IN SOLITARY PULMONARY NODULES WITH DYNAMIC CONTRAST-ENHANCED MRI |
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| Authors: | YANG Chun-shan XIAO Xiang-sheng LIU Shi-yuan LI Shen-jiang LI Hui-min LI Cheng-zhou |
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| Institution: | YANG Chun-shan(PET-CT Center, PLA 455 Hospital, Shanghai 200052, China)；XIAO Xiang-sheng(Department of Radiology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China)；LIU Shi-yuan(Department of Radiology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China)；LI Shen-jiang(Department of Radiology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China)；LI Hui-min(Department of Radiology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China)；LI Cheng-zhou(Department of Radiology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China)； |
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| Abstract: | Objective To evaluate the efficacy of contrast enhanced dynamic MRI in differentiating solitary pulmonary nodules(SPNs). Methods Eighty-three patients with SPNs undertaken contrast enhanced dynamic MRI. Time-signal intensity curve (T-SI Curve) was made. Peak height (PH), steepest slope (SS), maximum enhancement (Emax) and the enhancement rates of signal intensity were recorded at the first ( E1 ), second ( E2 ),third (E3) , fourth ( E4), fifth (E5) , and sixth (E6) minute after injection. Results Malignant nodules and inflammatory nodules enhanced significantly higher than benign nodules, and malignant nodules and inflammatory nodules showed obviously higher PH, SS, Emax, E1-E6 values than benign nodules( P ＜ 0. 01 ). There were no significant differences in PH, SS, E E1-E6 values between malignant nodules and inflammatory nodules( P ＞ 0. 05 ).Conclusion Contrast enhanced dynamic MR imaging can provide SPNs' hemodynamic information and is helpful in differentiating SPNs. |
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