STUDY OF AIRBORNE INSECT ALLERGEN IN ASTHMATIC PATIENTS

Airborneinsectsbelongtovectorinsectsandmaybringonspreadingofepidemicdiseasesorleadtoallergicdisease1] .Therelationshipbetweenair borneinsectandbronchialasthmahasbeenregardedbymoreandmoreallergistsrecently ;moreoversomepeopleconsiderthattheroleofairborneinsectsinetiologyofasthmaisnotinferiortothatofpollen ,fungusanddustmite2 ,3] .Thisstudyistolearnaboutthevarietyofairborneallergenicin sects,toprovidenewevidenceforstudyingetiologyofasthmaandfindnewwaystopreventandcureasthma .MATERIALSANDM…

STUDY OF AIRBORNE INSECT ALLERGEN IN ASTHMATIC PATIENTS

Objective To study the va ri ety of airborne allergenic insects and its sensibility in asthmatic patients. Methods 300 asthmatic patients and 100 normal controls underwent skin prick test (SPT) with 13 kinds of superior airborne insect vaccine, and ser a sIgE of those whose SPT results were positive were tested by BSA-ELISA. Results The total positive rate of SPT with 13 kinds of insect vacci ne in asthmatic patients was 58%, and it was significantly higher than that of n ormal control (P<0.01). The results of SPT with Stayridae, Heliothis armiger a, Psilgramma menephorn and other 7 kinds of insects were more than 30% in asthm atic patients which meant these 10 kinds of insects were main allergenic insects to asthmatic patients. The positive rate of sIgE in asthmatic patients was more than 85%, while the normal control was only 6.0%. There was significant differe nce between two groups (P<0.01). Conclusion Stayridae, Heliothis armigera, Psilgramma menephorn and other 7 kinds of insects were main allergenic insects to asthmatic patients and perhaps they were the main allergen s to the onset of asthma at the end summer or the early autumn.