| 多抗乙素与环磷酰胺、顺铂联用的抑瘤效果 |
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| 引用本文： | 徐长福,司履生,方亮.多抗乙素与环磷酰胺、顺铂联用的抑瘤效果[J].西安交通大学学报(医学版),1991(3). |
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| 作者姓名： | 徐长福 司履生 方亮 |
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| 作者单位： | 西安医科大学病理解剖学教研室
(徐长福，司履生)，西安医科大学病毒学研究室(方亮) |
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| 摘 要： | 多抗乙素是自乙型链球菌培养液中提取的一种生物反应调节剂,我们用患有进展期S-180肉瘤的小鼠进行实验证实,多抗乙素对S-180肉瘤有肯定的抑菌作用,能防止肺转移发生,使部分小鼠肿瘤痊愈(治愈率28%)。多抗乙素与顺铂联用,其抑瘤效果更佳。
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| 关 键 词： | 多抗乙素 生物反应调节剂 肿瘤化疗 S—180肉瘤 |
THE SUPPRESSION EFFECT OF DUOKANGYISU, CYCLOPHOSPHAMIDE AND CIS-PLATINUM COMBINATION THERAPY ON S180 SARCOMA |
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| Xu Chang Fu,Si Lusheng,Fang Ling.THE SUPPRESSION EFFECT OF DUOKANGYISU, CYCLOPHOSPHAMIDE AND CIS-PLATINUM COMBINATION THERAPY ON S180 SARCOMA[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1991(3). |
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| Authors: | Xu Chang Fu Si Lusheng Fang Ling |
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| Institution: | Xu Chang Fu;Si Lusheng;Fang Ling Department of pathology |
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| Abstract: | Duokangyisu is a newly beveloped biological re-sponse modifier, extracted from cultred βstreptococcus. Our experiment on mice bearing the ad-vanced S-180 sarcoma (day11 after S180 sarcoma inocula-tion showed that Duokangyisu could strongly suppessthe growth of S-180 sarcoma, prevent iung metastasis,and cure the tumor in some mice(cure rate 28%). Theeffect of tumor suppression would be enhanced whenDuokangyisu trcatment combined Cis--platinum. |
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| Keywords: | biological response modifier duokangyisu antineoplastic drug chemotherapy S-180 sarcoma |
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