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Validated LC-MS/MS method for simultaneous determination of SIM and its acid form in human plasma and cell lysate: Pharmacokinetic application
作者姓名:Tamer A. Ahmed  Jamie Horn  John Hayslip  Markos Leggas
摘    要:

关 键 词:细胞裂解液  药代动力学  SIM卡  LC-MS  同时测定  人血浆  MS法  应用

Validated LC-MS/MS method for simultaneous determination of SIM and its acid form in human plasma and cell lysate: Pharmacokinetic application
Tamer A. Ahmed,Jamie Horn,John Hayslip,Markos Leggas.Validated LC-MS/MS method for simultaneous determination of SIM and its acid form in human plasma and cell lysate: Pharmacokinetic application[J].Academic Journal of Xi’an Jiaotong University,2012,2(6).
Institution:1. Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 South Limestone Avenue, Lexington, Kentucky 40536-0596, USA
2. Markey Cancer Center, University of Kentucky, 800 Rose Street, Lexington, Kentucky 40536-0293, USA
3. Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 South Limestone Avenue, Lexington, Kentucky 40536-0596, USA Markey Cancer Center, University of Kentucky, 800 Rose Street, Lexington, Kentucky 40536-0293, USA
Abstract:
Keywords:Simvastatin  LC-MS/MS  Human plasma  Cell lysate  Pharmacokinetic  High-dose
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