| THE CHANGES OF BONE MINERAL DENSITY IN PATIENTS WITH HYPOPARATHYROIDISM |
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| 引用本文： | 马秀萍,施秉银,姚孝礼. THE CHANGES OF BONE MINERAL DENSITY IN PATIENTS WITH HYPOPARATHYROIDISM[J]. 西安交通大学学报(英文版), 1997, 0(1) |
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| 作者姓名： | 马秀萍 施秉银 姚孝礼 |
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| 作者单位： | Dept- of Endocrinology，First Affiliated Hospital，Xi'an Medical University，Xi'an710061 |
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| 摘 要： | Parathyroidhormone(PTH)isoneoftheimportantregu1atorsofcalciummetab0lisminthehumanbody.Itspro-ductionandsecretionaremainlyregulatedbyserumcalcium,calcitonin(CT),andl,25-dihydoxycholecacifer0l.Itsphysiologi-caleffectsarepr0m0ti0nofphosphorusdischargefromkidney,acceleration0fboneturn0ver,mobi1izingskelet0ncalciumintocirculation,andactivati0nofvitaminD.Manystudiespr0vedthatprimaryhy-perparathyroidismcausedosteopeniawhichwaspartiallyreversiblebyparathyroidsurgery"'.Hyp0parathyroidismisarela-tive…
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THE CHANGES OF BONE MINERAL DENSITY IN PATIENTS WITH HYPOPARATHYROIDISM |
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| Ma Xiuping,Shi Bingyin,Yao Xiaoli. THE CHANGES OF BONE MINERAL DENSITY IN PATIENTS WITH HYPOPARATHYROIDISM[J]. Academic Journal of Xi’an Jiaotong University, 1997, 0(1) |
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| Authors: | Ma Xiuping Shi Bingyin Yao Xiaoli |
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| Abstract: | This study observed the changes of BMD, serum calcium, bone Gla protein and calcitonin of patients with hypoparathyroidism controlled by age and sex matched healthy persons. It was found that BMD was 10% greater in hypoparathyroidism patients than in controls, but the difference was not statistically significant. Serum BGP was significantly lower in hypoparathyroidism patients than in controls (P<0. 02). We postulate that PTH deficiency and long term treatment with calcium and vitamin D for hypoparathyroidism appear to be main mediator of this increased bone mass,and that hone mass is not affected by endogenous calcitonin. |
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| Keywords: | Hypoparathyroidism bone mineral density bone Gla protein calcitonin |
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