Guillain-Barre综合征早期电生理变化及分型再认识

分析了31例Guillain－Barre综合征（GBS）的电生理改变。有14例于病后3周行肌电图检查。早期运动神经传导速度（MCV）异常率为71．01％，主要表现为末端潜伏时（ML）延长，占61．22％，其次为MCV轻度减慢，而感觉神经传导速度（SCV）及肌电图（EMG）对早期GBS的诊断价值有限．但EMG鼻常出现越早，则预后越差。31例电生理特点分型：髓鞘型GBS27例（87．09％），轴索型GBS2例（6．4％），另有2例（6．4％）髓鞘及轴索损害均较重，预后差，故认为可能是两者同时损害的混合型。

FURTHER RESEARCH INTO GUILLAIN-BARRE SYNDROME'S EARLY ELECTROPHYSIOLOGICAL CHANGE AND CATEGORY

Some new points about electrophysi-ological feature and classification in early stage have been found in this article. The abnormality rate of MCV in the early stage was 71. 01 %. In the abnor-mal change, 61. 22% showed a prolonged on ML first. Secondly it was a slightly slow on MCV, SCV and EMG have little importance in GBS,s early diag-nosis, the earlier the occurring of abnormal EMG,the poorer the prognosis. According to the electro-physiological characteristics, 27 cases (87. 08%)could be classified as a myelin sheath GBS, two cas-es (6. 4% ) could be classified as a neuraxis GBS; the other two cases (6. 4 % ) with almost the same dam-age to myelin sheath and neuraxis, and a poor prog-nosis among 31 cases. The latter two cases have never been reported, they could be a subcategory which will need to be studied.