| 神经毒对大鼠三叉神经节神经元的影响 |
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| 引用本文： | 张可仁,陈玉华,宋彤,杜希哲,芮瑜,马菊芬.神经毒对大鼠三叉神经节神经元的影响[J].西安交通大学学报(医学版),1986(3). |
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| 作者姓名： | 张可仁 陈玉华 宋彤 杜希哲 芮瑜 马菊芬 |
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| 作者单位： | 西安医科大学系统解剖学教研室
(张可仁)，西安医科大学卫生学教研室
(陈玉华)，西安医科大学第二附属医院
(宋彤)，西安医科大学第一附属医院
(杜希哲，芮瑜)，西安医科大学系统解剖学教研室(马菊芬) |
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| 摘 要： | 本文用29只大鼠分别注射二硫化碳、苯、氯化高汞饱和液、醋酸铅饱和液、纯酒精于一侧眶下神经,在光镜和电镜下观察了三叉神经节细胞的变化。观察结果证明这些神经毒经神经节细胞周围突逆行作用于胞体,使胞体产生不同的病理变化。用同样的方法注射生理盐水和切断眶下神经,证明神经节细胞的变化不是张力和机械损伤所致而是中毒的结果。
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EFFECT OF NEUROTOXIN ON NEURON OF TRIGENMINAL GANGLION IN RATS |
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| Zhang Keren,et al.EFFECT OF NEUROTOXIN ON NEURON OF TRIGENMINAL GANGLION IN RATS[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1986(3). |
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| Authors: | Zhang Keren |
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| Institution: | Xi'an Medical University |
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| Abstract: | After carbon bisulfide, benzol, lead acetate saturation fluid, mercurric bichloride saturation fluid and alcohol were injected respectively in the infraorbital nerve on one side in 29 adult rats, the pathological changes in trigeminal ganglion were studied microscopically and electromicroscopically. The results showed these neurotoxins had a retrograde effect on the cell body through the peripheral process of ganglion cell, inducing different pathological changes in cell body. In addition, we studied the slices using the method mentioned above, after physiological saline solution was injected in the infraorbital nerve or it was cut. It was proved that the pathological changes of ganglion cell in the first experiment were not induced by the change of tension or mechanical damage. They were the result of poisoning as compared with the result of the second experiment. |
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| Keywords: | trigeminal ganglion infraorbital nerve carbon bisulfide benzol lead acetete mercury bichloride alcohol |
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